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NCR3LG1 wt Allele

Known as: B7-H6, Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 wt Allele, B7H6 
Human NCR3LG1 wild-type allele is located in the vicinity of 11p15.1 and is approximately 26 kb in length. This allele, which encodes natural… 
National Institutes of Health

Related topics

Related topics

4 relations
11p15.1Ligand BindingNK Cell Activationprotein protein interaction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
The B7 Family Member B7-H6: a New Bane of Tumor
B7-H6 is a ligand of NKp30, which is an activating receptor of natural killer (NK) cells. High expression of B7-H6 is found in… 
2018
2018
B7‐H6 expression is induced by lipopolysaccharide and facilitates cancer invasion and metastasis in human gliomas
2016
2016
The proto-oncogene Myc drives expression of the NK cell-activating NKp30 ligand B7-H6 in tumor cells
ABSTRACT Natural Killer (NK) cells are innate effector cells that are able to recognize and eliminate tumor cells through… 
Highly Cited
2015
Highly Cited
2015
Tumor Therapeutics Work as Stress Inducers to Enhance Tumor Sensitivity to Natural Killer (NK) Cell Cytolysis by Up-regulating NKp30 Ligand B7-H6*
Background: B7-H6, the ligand for NKp30, is expressed on tumor cells. Results: Tumor therapeutics promote B7-H6 expression in… 
Highly Cited
2015
Highly Cited
2015
B7-H6 expression correlates with cancer progression and patient's survival in human ovarian cancer.
B7-H6, a newly identified B7 family member molecule, binds to its receptor on NK cells, NKp30, and then triggers the anti-tumor… 
2015
2015
B7H6-specific chimeric antigen receptors lead to tumor elimination and host anti-tumor immunity
Chimeric antigen receptor (CAR) T-cell therapies have demonstrated durable and potentially curative therapeutic efficacy against… 
Highly Cited
2014
Highly Cited
2014
Metalloprotease-mediated tumor cell shedding of B7-H6, the ligand of the natural killer cell-activating receptor NKp30.
Natural killer (NK) cells are potent immune effector cells capable of mediating antitumor responses. Thus, during immunoediting… 
Review
2013
Review
2013
The role of B7 family molecules in hematologic malignancy.
The B7 family consists of structurally related, cell-surface proteins that regulate immune responses by delivering costimulatory… 
Highly Cited
2013
Highly Cited
2013
Downregulation of the activating NKp30 ligand B7-H6 by HDAC inhibitors impairs tumor cell recognition by NK cells.
Natural killer (NK) cells are central effector cells during innate immune responses against cancer. Natural cytotoxicity… 
Highly Cited
2013
Highly Cited
2013
Induction of B7-H6, a ligand for the natural killer cell-activating receptor NKp30, in inflammatory conditions.
B7-H6, a member of the B7 family of immunoreceptors, is as a cell-surface ligand for the NKp30-activating receptor expressed on… 
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