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NC 1300
Known as:
NC-1300
National Institutes of Health
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Papers overview
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1993
1993
NC-1300, a proton-pump inhibitor, requires gastric acid to exert cytoprotection in rat gastric mucosa.
T. Arakawa
,
T. Fukuda
,
K. Higuchi
,
K. Koike
,
H. Satoh
,
K. Kobayashi
Japanese Journal of Pharmacology
1993
Corpus ID: 40254206
Effect of gastric acid suppression on the cytoprotective effect of a single dose of NC-1300 given intragastrically was studied…
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1992
1992
Effects of proton pump inhibitor on gastric mucosa hemodynamics and tissue oxygenation in anesthetized rats.
S. Kawano
,
H. Tanimura
,
+6 authors
T. Kamada
European Journal of Pharmacology
1992
Corpus ID: 31775881
1989
1989
Pathogenesis of the earliest epithelial cell damage induced by mepirizole and cysteamine in the rat duodenum.
H. Tanaka
,
K. Takeuchi
,
S. Okabe
,
M. Murakami
Japanese Journal of Pharmacology
1989
Corpus ID: 33894379
Mepirizole (200 mg/kg) and cysteamine (100 mg/kg) induced epithelial cell damage in the proximal duodenum of rats within 30 min…
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1989
1989
Effects of NC-1300, a gastric proton pump inhibitor, on healing of acetic acid-induced gastric ulcers in rats
S. Okabe
,
H. Miyake
,
S. Yamasaki
Digestive Diseases and Sciences
1989
Corpus ID: 31308445
Effects of NC-1300 (a gastric proton pump inhibitor) on healing of experimental chronic gastric ulcers induced in rats were…
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1989
1989
Effect of the proton pump inhibitor, NC-1300, on gastric mucus secretion in rats.
S. Ohara
,
H. Ohkawa
,
K. Ishihara
,
K. Hotta
,
Y. Komuro
,
H. Okabe
Scandinavian Journal of Gastroenterology…
1989
Corpus ID: 33321578
The effects of NC-1300 on gastric acid and mucus glycoprotein secretion were investigated in pylorus-ligated (4 h) rats. NC-1300…
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1989
1989
Histamine-induced villous damage in the rat duodenum.
H. Tanaka
,
K. Takeuchi
,
S. Okabe
Japanese Journal of Pharmacology
1989
Corpus ID: 10132657
A single s.c. administration of histamine dose-dependently (5-20 mg/kg) induced villous damage of the proximal duodenum in 24-hr…
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1988
1988
The effect of a new gastric proton pump inhibitor on serotonin-induced gastric mucosal lesions in rats
Y. Tsukamoto
,
S. Nakazawa
,
+7 authors
Y. Kawabe
Gastroenterologia Japonica
1988
Corpus ID: 37259131
SummaryThe anti-ulcer effect of NC-1300, a new proton pump inhibitor, and its effect on gastric mucosal blood flow were studied…
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1987
1987
Effects of NC-1300 and its degradation products on gastric secretion and HCl.ethanol-induced gastric lesions in rats.
Susumu Okabe
,
Y. Akimoto
,
Hiroki Miyake
,
Junko Imada
Japanese Journal of Pharmacology
1987
Corpus ID: 24515800
The proton pump inhibitor NC-1300 has antisecretory and cytoprotective activities in rats. The compound is labile at an acidic pH…
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1986
1986
Biochemical and pharmacological analysis of 2-[(2-dimethylaminobenzyl)sulfinyl] benzimidazole (NC-1300), a new proton pump inhibitor.
S. Okabe
,
E. Higaki
,
T. Higuchi
,
M. Sato
,
K. Hara
Japanese Journal of Pharmacology
1986
Corpus ID: 43705271
Biochemical and pharmacological properties of a newly synthesized compound, 2-[(2-dimethylaminobenzyl)sulfinyl] benzimidazole (NC…
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Review
1986
Review
1986
[Effects of gastric proton pump inhibitors on gastric secretion and peptic ulcers].
S. Okabe
Nihon yakurigaku zasshi. Folia pharmacologica…
1986
Corpus ID: 38886111
This is a review article on newly developed antisecretory drugs which are now called proton pump inhibitors. Gastric H+ is…
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