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NAD+ kinase activity

Known as: nicotinamide adenine dinucleotide kinase (phosphorylating), nicotinamide adenine dinucleotide kinase activity, NADK 
Catalysis of the reaction: ATP + NAD(+) = ADP + 2 H(+) + NADP(+). [EC:2.7.1.23, RHEA:18632]
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Episodic evolution of a eukaryotic NADK repertoire of ancient provenance
NAD kinase (NADK) is the sole enzyme that phosphorylates nicotinamide adenine dinucleotide (NAD+/NADH) into NADP+/NADPH, which… 
2012
2012
A second target of benzamide riboside
Dihydrofolate reductase (DHFR) is an essential enzyme involved in de novo purine and thymidine biosynthesis. For several decades… 
2011
2011
Synthesis and Enzymatic Evaluation of NAD Mimics as Nicotinamide Adenine Dinucleotide Kinase (NADK) Inhibitors
Highly Cited
2009
Highly Cited
2009
Pleiotropic Modulation of Carbon and Nitrogen Metabolism in Arabidopsis Plants Overexpressing the NAD kinase2 Gene1[W]
Nicotinamide nucleotides (NAD and NADP) are important cofactors in many metabolic processes in living organisms. In this study… 
Review
2009
Review
2009
NAD(P) biosynthesis enzymes as potential targets for selective drug design.
NAD(P) biosynthetic pathways can be considered a generous source of enzymatic targets for drug development. Key reactions for NAD… 
2004
2004
Cloning and Characterization of Two NAD Kinases from Arabidopsis . Identification of a Calmodulin Binding Isoform 1
NAD kinase (NADK; ATP:NAD 2#-phosphotransferase, EC 2.7.1.23), an enzyme found in both prokaryotes and eukaryotes, generates the… 
2003
2003
Effect of selected phytotoxins from Guanomyces polythrix on the calmodulin-dependent activity of the enzymes cAMP phosphodiesterase and NAD-kinase.
The effect of a series of phytotoxins isolated from the fungus Guanomyces polytrix on calmodulin (CaM)-dependent nicotinamide… 
2001
2001
Developmental ontogeny of NAD+ kinase in the rat conceptus.
The ubiquitous NAD+ kinase (NADK) is the only known enzyme to catalyze formation of NADP+ from NAD+. The capacity to maintain an… 
1996
1996
Oxidation of NADH catalysed by human xanthine oxidase: generation of superoxide anion.
Xanthine Oxidase is of importance because of its potential to generate superoxide anion and hydrogen peroxide; reactive oxygen… 
1986
1986
NADP+ production using thermostable NAD+ kinase of corynebacterium flaccumfaciens AHU-1622.
A sonicate of Corynebacterium flaccumfaciens AHU-1622 had the highest NAD+ kinase activity (1.22 mU/mL culture broth) of the… 
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