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The human N-terminal acetyltransferase E (NatE) contains NAA10 and NAA50 catalytic, and NAA15 auxiliary subunits and associates… Expand NatA co-translationally acetylates the N termini of over 40% of eukaryotic proteins and can associate with another catalytic… Expand N-Terminal acetylation is a common and important protein modification catalyzed by N-terminal acetyltransferases (NATs). Six… Expand During the cell cycle, sister-chromatid cohesion tethers sister chromatids together from S phase to the metaphase-anaphase… Expand Cotranslational N‐terminal (Nt‐) acetylation of nascent polypeptides is mediated by N‐terminal acetyltransferases (NATs). The… Expand Significance Each heartbeat originates in the sinoatrial node (SAN), a collection of specialized cardiomyocytes (SANCs), which… Expand The X-linked lethal Ogden syndrome was the first reported human genetic disorder associated with a mutation in an N-terminal… Expand The definitive sinoatrial node (SAN), the primary pacemaker of the mammalian heart, develops from part of pro-pacemaking… Expand Protein acetylation is a widespread modification that is mediated by site-selective acetyltransferases. KATs (lysine N… Expand Gene activation in eukaryotes is regulated by complex mechanisms in which the recruitment and assembly of the transcriptional… Expand