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N1'-carboxybiotin

Known as: 1H-thieno(3,4-d)imidazole-4-pentanoic acid, 1-carboxyhexahydro-2-oxo-, (3aS-(3a alpha,4 beta,6a alpha))-, carboxybiotin 
National Institutes of Health

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2 relations

Broader (1)

Biotin
analogs & derivatives

Papers overview

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2010
2010
I'm a PC (Pyruvate Carboxylase)…and diabetes was not my idea!
NIH estimates that 23 million Americans have diabetes, and 6.2 million are undiagnosed. If untreated, diabetes can cause… 
2002
2002
Figure 16.27, Structure of Carboxybiotin
1986
1986
Studies on biotin dependent carboxylases and the properties of carboxybiotin
Biotin dependent carboxyl-transfer reactions have been studied using biotin and pyruvate carboxylases. The pH profile for the Mg… 
1981
1981
Factors thatinfluence thetranslocation oftheN-carboxybiotin moiety between thetwosub-sites ofpyruvate carboxylase
Theactive site ofpyruvate carboxylase, like those ofall biotin-dependent carboxylases, isbelieved toconsist oftwospatially… 
1976
1976
Magnetic resonance studies of the proximity and spatial arrangement of propionyl coenzyme A and pyruvate on a biotin-metalloenzyme, transcarboxylase.
A spin-labeled ester of CoA, R-CoA (3-carboxy-2,2,5,5-tetramethyl-1-pyrolidinyl-1-oxy CoA thioester), has been shown by… 
1966
1966
Studies on the mechanism of action of acetyl coenzyme A carboxylase. 3. Enzyme-bound 1'-N-carboxybiotin as the carboxylation intermediate.
Abstract Studies presented here, with the criterion of the degree of binding of the biotin derivatives obtained from acetyl…