N-methylhistamine

As a part of our search for novel histamine H3 receptor agonists, we designed and synthesized hybrid compounds in which the… (More)

Target-based high-throughput screening (HTS) plays an integral role in drug discovery. The implementation of HTS assays generally… (More)

The pharmacology of histamine H(3) receptors suggests the presence of distinct receptor isoforms or subtypes. We herein describe… (More)

The role of central and peripheral histamine H3 receptors in the regulation of gastric acid secretion and gastric mucosal… (More)

A gas chromatography-electron capture mass spectrometry assay has been developed for the histamine H3 receptor agonist, N(alpha… (More)

In this review the histaminergic ligands for the histamine H(1), H(2) and H(3) receptors, which are currently used as tools in… (More)

The activation of presynaptic histamine 3 (H(3)) receptors inhibits the release of histamine and other neurotransmitters from… (More)

Histamine elicits its biological effects via three distinct G protein-coupled receptors, termed H1, H2, and H3. We have used… (More)

Activation of histamine H3 receptors by histamine (0.1 to 10 microM), (R)alpha-methylhistamine and N(alpha)-methylhistamine (0.01… (More)

The effects of histamine and N(alpha)-methylhistamine, two components of gastric juice, on vagal and transmural stimulation of… (More)