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N-hydroxyxanthine

Known as: 3,7-dihydro-3-hydroxy-1H- purine-2,6-dione, 3-hydroxyxanthine 
 
National Institutes of Health

Papers overview

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1978
1978
Injection s.c. of purine 3-oxide into Wistar rats resulted in the appearance of sarcomas and fibromas at the interscapular site… Expand
1977
1977
Diethyldithiocarbamate (DEDTC) prevented dimethylnitrosamine (DMN)-induced strand breaks in liver DNA and liver cell necrosis in… Expand
1975
1975
Using alkaline and neutral sucrose gradients, it was observed that administration of the hepatocarcinogen, 3-hydroxyxanthine, to… Expand
1975
1975
A technique involving O-acetylation of purine N-oxide derivatives in buffered aqueous solutions has permitted studies of the… Expand
1973
1973
Summary Comparative assays of the oncogenicities of a series of N -methyl and other derivatives of 3-hydroxyxanthine and 3… Expand
1972
1972
The oncogen 3-hydroxyxanthine is enzymatically converted to a chemically reactive form by a protein fraction of the 100,000 × g… Expand
1970
1970
Assays of the oncogenic N -oxide derivatives of xanthine and guanine, which have now been proven to be 3-hydroxyxanthine and… Expand
1970
1970
Two additional urinary metabolites of the chemical oncogen 3-hydroxyxanthine are now identified as 8-chloroxanthine and 8… Expand
1970
1970
The oncogenicity of the purine N -oxide, 3-hydroxyxanthine, was tested in newborn and weanling ICR/Ha mice and in newborn… Expand
1969
1969
Abstract The major metabolites found in the urine after administration of 3-hydroxyxanthine-8-14C to rats are 3-hydroxyuric acid… Expand