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N-hydroxyxanthine

Known as: 3,7-dihydro-3-hydroxy-1H- purine-2,6-dione, 3-hydroxyxanthine 
National Institutes of Health

Papers overview

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1978
1978
Injection s.c. of purine 3-oxide into Wistar rats resulted in the appearance of sarcomas and fibromas at the interscapular site… 
1978
1978
The oncogenicities of all of the four possible isomeric N -hydroxyxanthines have been compared. For the two that were active, the… 
1977
1977
Diethyldithiocarbamate (DEDTC) prevented dimethylnitrosamine (DMN)-induced strand breaks in liver DNA and liver cell necrosis in… 
1973
1973
Summary Comparative assays of the oncogenicities of a series of N -methyl and other derivatives of 3-hydroxyxanthine and 3… 
1972
1972
The oncogen 3-hydroxyxanthine is enzymatically converted to a chemically reactive form by a protein fraction of the 100,000 × g… 
1970
1970
Assays of the oncogenic N -oxide derivatives of xanthine and guanine, which have now been proven to be 3-hydroxyxanthine and… 
1970
1970
Two additional urinary metabolites of the chemical oncogen 3-hydroxyxanthine are now identified as 8-chloroxanthine and 8… 
1970
1970
The oncogenicity of the purine N -oxide, 3-hydroxyxanthine, was tested in newborn and weanling ICR/Ha mice and in newborn… 
1969
1969
Abstract The major metabolites found in the urine after administration of 3-hydroxyxanthine-8-14C to rats are 3-hydroxyuric acid…