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N-hydroxyphenacetin glucuronide

Known as: beta-D-Glucopyranuronic acid, 1-((acetyl(4-ethoxyphenyl)amino)oxy)-1-deoxy-, phenacetin N-O-glucuronide 
National Institutes of Health

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Phenacetin
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1993
1993
Induction of renal pelvic carcinoma by phenacetin in hydronephrosis-bearing rats of the SD/cShi strain.
Carcinogenicity of phenacetin (PH) to the urinary tract was tested with the use of spontaneously hydronephrosis-bearing rats. In… 
1987
1987
Metabolic activation of phenacetin and phenetidine by several forms of cytochrome P-450 purified from liver microsomes of rats and hamsters.
Metabolic activation of phenacetin by liver microsomes proceeds via both phenetidine and N-hydroxyphenacetin to direct-acting… 
1985
1985
Metabolism and nephrotoxicity of phenacetin and sulfanilamide.
The mechanisms of renal damage produced by sulfanilamide and phenacetin were studied. N-Hydroxyphenacetin, 4… 
1985
1985
The metabolism of N-hydroxyphenacetin in vitro and in vivo.
N-Hydroxyphenacetin (100 mg/kg) injected i.p. into rats rapidly appeared in the blood and disappeared with a t1/2 of 14 min… 
1984
1984
N-Hydroxy-N-arylacetamides
Abstract1.Of the two carcinogenic N-hydroxy-N-arylacetamides tested, N-hydroxy-4-acetylaminobiphenyl was as active as the… 
1981
1981
Activation of N-hydroxyphenacetin to mutagenic and nucleic acid-binding metabolites by acyltransfer, deacylation, and sulfate conjugation.
N-Hydroxyphenacetin was activated to a mutagen in the Salmonella-Ames test by rabbit liver acyltransferase, rat liver cytosol… 
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