N-demethyltramadol hydrochloride
National Institutes of Health
Papers overview
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OBJECTIVE
To evaluate the analgesic potential of the centrally acting analgesics tramadol, morphine and the novel analgesic…
The Thai medicinal plant Mitragyna speciosa (kratom) is misused as a herbal drug. Besides this, a new herbal blend has appeared…
The kinetics of tramadol enantiomers are stereoselective when doses of the racemic drug are given orally. To document whether the…
Dear Professor Dahlqvist, We read with interest the article by Fliegert et al. published online on May 20 that describes…
In this study the role of cytochrome P450 2D (CYP2D) in the pharmacokinetic/pharmacodynamic relationship of (+)-tramadol [(+)-T…
AIM
To study the stereoselectivity in O-demethylation of trans tramadol.
METHODS
With or without quinine and quinidine as…
A sensitive and stereoselective high-performance liquid chromatographic assay for the quantitative determination of the analgesic…
In in vitro receptor binding and synaptosomal uptake experiments the (+)-enantiomer of tramadol (CAS 148229-78-1) is specific for…