N-demethyltramadol hydrochloride
National Institutes of Health
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The aim of this study was to compare the pharmacokinetic profile and oral bioavailability of Tramadol Contramid once-daily (o.d…
AIM
To study the stereoselectivity in O-demethylation of trans tramadol.
METHODS
With or without quinine and quinidine as…
AIM
To study the stereoselectivity in renal clearance of trans-tramadol and its active metabolite, trans-O-demethyltramadol…
AIM
To investigate the transportation of the enantiomers of trans tramadol (trans T) and its active metabolite, O…
Aim To study the plasma protein binding of the enantiomers of trans tramadol (trans T) and its active metabolite, O…
OBJECTIVE: To establish a method for determining the enantiomers of (±)-trans tramadol ((±)-trans T) and (±)-trans O…