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N,N-didesmethyl-4-hydroxytamoxifen

Known as: norendoxifen 
 
National Institutes of Health

Papers overview

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2018
2018
Norendoxifen, an active metabolite of tamoxifen, is a potent aromatase inhibitor. Little information is available regarding… Expand
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2016
2016
AIM The aim was to examine the influence of CYP2C19 variants and associated haplotypes on the disposition of tamoxifen and its… Expand
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2016
2016
The design and synthesis of dual aromatase inhibitors/selective estrogen receptor modulators (AI/SERMs) is an attractive strategy… Expand
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2016
2016
The tamoxifen-inducible Cre-loxP system is widely used to overcome gene targeting pre-adult lethality, to modify a specific cell… Expand
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Highly Cited
2015
Highly Cited
2015
Tamoxifen is the standard-of-care treatment for estrogen receptor-positive premenopausal breast cancer. We examined tamoxifen… Expand
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2015
2015
Both selective estrogen receptor modulators and aromatase inhibitors are widely used for the treatment of breast cancer… Expand
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2013
2013
The first synthesis of the tamoxifen metabolite norendoxifen is reported. This included syntheses of (E)-norendoxifen, (Z… Expand
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2013
2013
Aromatase catalyzes the conversion of testosterone to estradiol and is the main source of endogenous estrogen in postmenopausal… Expand
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Review
2013
Review
2013
Tamoxifen, a selective estrogen receptor modulator, is important for the treatment and prevention of estrogen receptor (ER… Expand
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2011
2011
To improve the treatment of breast cancer, there has been a need for alternative aromatase inhibitors (AIs) that bring about… Expand
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