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N,N-didesmethyl-4-hydroxytamoxifen

Known as: norendoxifen 
National Institutes of Health

Papers overview

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2018
2018
Norendoxifen, an active metabolite of tamoxifen, is a potent aromatase inhibitor. Little information is available regarding… 
2016
2016
The tamoxifen-inducible Cre-loxP system is widely used to overcome gene targeting pre-adult lethality, to modify a specific cell… 
2016
2016
AIM The aim was to examine the influence of CYP2C19 variants and associated haplotypes on the disposition of tamoxifen and its… 
Highly Cited
2015
Highly Cited
2015
Tamoxifen is the standard-of-care treatment for estrogen receptor-positive premenopausal breast cancer. We examined tamoxifen… 
2015
2015
Both selective estrogen receptor modulators and aromatase inhibitors are widely used for the treatment of breast cancer… 
Review
2013
Review
2013
Tamoxifen, a selective estrogen receptor modulator, is important for the treatment and prevention of estrogen receptor (ER… 
2013
2013
The first synthesis of the tamoxifen metabolite norendoxifen is reported. This included syntheses of (E)-norendoxifen, (Z… 
2013
2013
Aromatase catalyzes the conversion of testosterone to estradiol and is the main source of endogenous estrogen in postmenopausal… 
Highly Cited
2011
Highly Cited
2011
To improve the treatment of breast cancer, there has been a need for alternative aromatase inhibitors (AIs) that bring about…