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N,N-didesmethyl-4-hydroxytamoxifen

Known as: norendoxifen 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Tamoxifen
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
The Cytochrome P450 Enzyme Responsible for the Production of (Z)‐Norendoxifen in vitro
Norendoxifen, an active metabolite of tamoxifen, is a potent aromatase inhibitor. Little information is available regarding… 
Highly Cited
2016
Highly Cited
2016
Tamoxifen in the Mouse Brain: Implications for Fate-Mapping Studies Using the Tamoxifen-Inducible Cre-loxP System
The tamoxifen-inducible Cre-loxP system is widely used to overcome gene targeting pre-adult lethality, to modify a specific cell… 
2016
2016
Association of CYP2C19*2 and associated haplotypes with lower norendoxifen concentrations in tamoxifen-treated Asian breast cancer patients.
AIM The aim was to examine the influence of CYP2C19 variants and associated haplotypes on the disposition of tamoxifen and its… 
2016
2016
A new Suzuki synthesis of triphenylethylenes that inhibit aromatase and bind to estrogen receptors α and β.
2016
2016
Abstract P5-12-09: A novel commercial LC-MS/MS assay for tamoxifen (TAM) and its major metabolites
The standard of care for women presenting with early stage- ER-positive breast cancer (BC) following "curative" surgery has been… 
2015
2015
Design and synthesis of norendoxifen analogues with dual aromatase inhibitory and estrogen receptor modulatory activities.
Both selective estrogen receptor modulators and aromatase inhibitors are widely used for the treatment of breast cancer… 
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