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Myosin Regulatory Light Chain

Known as: Myosin Regulatory Light Chains 
 
National Institutes of Health

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Myosin Light Chains

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Highly Cited
2016
Highly Cited
2016
Myosin light chain phosphorylation enhances contraction of heart muscle via structural changes in both thick and thin filaments
Significance Contraction of heart muscle is triggered by calcium binding to the actin-containing thin filaments but modulated by… Expand
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Highly Cited
2012
Highly Cited
2012
AMPK regulates mitotic spindle orientation through phosphorylation of myosin regulatory light chain.
The proper orientation of the mitotic spindle is essential for mitosis; however, how these events unfold at the molecular level… Expand
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Highly Cited
2012
Highly Cited
2012
Transcriptome characterization of estrogen-treated human myocardium identifies myosin regulatory light chain interacting protein as a sex-specific element influencing contractile function.
OBJECTIVES This study investigated the effects of 17β-estradiol (E2) on gene regulation in human cardiac tissues. We hypothesized… Expand
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Highly Cited
2009
Highly Cited
2009
Helicobacter pylori dysregulation of gastric epithelial tight junctions by urease-mediated myosin II activation.
BACKGROUND & AIMS Helicobacter pylori-induced gastritis predisposes to the development of gastric cancer. Increased epithelial… Expand
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Highly Cited
2005
Highly Cited
2005
ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles
Rho-associated kinase (ROCK) I mediates signaling from Rho to the actin cytoskeleton. To investigate the in vivo functions of… Expand
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Highly Cited
2004
Highly Cited
2004
Non-muscle Myosin II and Myosin Light Chain Kinase Are Downstream Targets for Vasopressin Signaling in the Renal Collecting Duct*
We have previously demonstrated that vasopressin increases the water permeability of the inner medullary collecting duct (IMCD… Expand
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Highly Cited
2003
Highly Cited
2003
Agonist-induced changes in the phosphorylation of the myosin- binding subunit of myosin light chain phosphatase and CPI17, two regulatory factors of myosin light chain phosphatase, in smooth muscle.
The inhibition of myosin light chain phosphatase (MLCP) enhances smooth muscle contraction at a constant [Ca2+]. There are two… Expand
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Highly Cited
2002
Highly Cited
2002
A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease.
BACKGROUND & AIMS Maintenance of the mucosal barrier is a critical function of intestinal epithelia. Myosin regulatory light… Expand
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Highly Cited
2001
Highly Cited
2001
Rho-Kinase–Mediated Contraction of Isolated Stress Fibers
It is widely accepted that actin filaments and the conventional double-headed myosin interact to generate force for many types of… Expand
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Highly Cited
1998
Highly Cited
1998
Apoptotic Membrane Blebbing Is Regulated by Myosin Light Chain Phosphorylation
The evolutionarily conserved execution phase of apoptosis is defined by characteristic changes occurring during the final stages… Expand
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