Myosin Light Chain Kinase

Known as: EC 2.7.11.18, smMLCK, Kinase-Related Protein 
An enzyme that phosphorylates myosin light chains in the presence of ATP to yield myosin-light chain phosphate and ADP, and requires calcium and… (More)
National Institutes of Health

Papers overview

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Review
2012
Review
2012
Dynamic regulation of paracellular permeability is essential for physiological epithelial function, while dysregulated… (More)
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Highly Cited
2010
Highly Cited
2010
Mutations in smooth muscle cell (SMC)-specific isoforms of α-actin and β-myosin heavy chain, two major components of the SMC… (More)
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Highly Cited
2006
Highly Cited
2006
The intestinal epithelial barrier is frequently disrupted in inflammatory bowel disease (IBD) and this has been proposed to play… (More)
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Highly Cited
2000
Highly Cited
2000
Phosphorylation of myosin II regulatory light chains (RLC) by Ca(2+)/calmodulin-dependent myosin light chain kinase (MLCK) is a… (More)
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Highly Cited
2000
Highly Cited
2000
Myofibroblasts generate the contractile force responsible for wound healing and pathological tissue contracture. In this paper… (More)
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Highly Cited
1999
Highly Cited
1999
p21-activated kinases (PAKs) are implicated in the cytoskeletal changes induced by the Rho family of guanosine triphosphatases… (More)
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Highly Cited
1997
Highly Cited
1997
Cell interaction with adhesive proteins or growth factors in the extracellular matrix initiates Ras/mitogen-activated protein… (More)
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Highly Cited
1995
Highly Cited
1995
The phosphorylation of regulatory myosin light chains by the Ca2+/calmodulin-dependent enzyme myosin light chain kinase (MLCK… (More)
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Highly Cited
1995
Highly Cited
1995
Endothelial cell (EC) contraction results in intercellular gap formation and loss of the selective vascular barrier to… (More)
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Highly Cited
1985
Highly Cited
1985
The 20,000-dalton light chain of turkey gizzard myosin is phosphorylated at two sites. Dual phosphorylation is observed when both… (More)
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