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Myosin Light Chain Kinase

Known as: EC 2.7.11.18, smMLCK, Kinase-Related Protein 
An enzyme that phosphorylates myosin light chains in the presence of ATP to yield myosin-light chain phosphate and ADP, and requires calcium and… 
National Institutes of Health

Related topics

Related topics

31 relations
Calpain-2 Cell Motility PathwayEnzyme GeneFocal adhesion pathwayHomo sapiens

Narrower (6)

M13 protein (myosin light-chain kinase)SM 1Speg protein, mouseStrn-Mlck protein, Drosophila

Papers overview

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Highly Cited
2010
Highly Cited
2010
Myosin light chain kinase mediates transcellular intravasation of breast cancer cells through the underlying endothelial cells: a three-dimensional FRET study
The transient and localized signaling events between invasive breast cancer cells and the underlying endothelial cells have… 
Highly Cited
2008
Highly Cited
2008
Identification of Cardiac-Specific Myosin Light Chain Kinase
Two myosin light chain (MLC) kinase (MLCK) proteins, smooth muscle (encoded by mylk1 gene) and skeletal (encoded by mylk2 gene… 
Review
2005
Review
2005
Regulation of myosin II during cytokinesis in higher eukaryotes.
Highly Cited
2000
Highly Cited
2000
Phosphorylation of Myosin Light Chain Kinase by p21-activated Kinase PAK2*
Phosphorylation of myosin II regulatory light chains (RLC) by Ca2+/calmodulin-dependent myosin light chain kinase (MLCK) is a… 
Highly Cited
1998
Highly Cited
1998
Apoptotic Membrane Blebbing Is Regulated by Myosin Light Chain Phosphorylation
The evolutionarily conserved execution phase of apoptosis is defined by characteristic changes occurring during the final stages… 
Highly Cited
1997
Highly Cited
1997
Unconventional Myosins in Inner-Ear Sensory Epithelia
To understand how cells differentially use the dozens of myosin isozymes present in each genome, we examined the distribution of… 
Highly Cited
1990
Highly Cited
1990
Regulatory and structural motifs of chicken gizzard myosin light chain kinase.
The amino acid sequence for chicken smooth muscle myosin light chain kinase (smMLCK) was deduced from a full-length cDNA. This… 
Highly Cited
1986
Highly Cited
1986
Calmodulin binding domains: characterization of a phosphorylation and calmodulin binding site from myosin light chain kinase.
A protein kinase phosphorylation site in chicken gizzard myosin light chain kinase (MLCK) has been identified, and a synthetic… 
Highly Cited
1978
Highly Cited
1978
Identification of an activator protein for myosin light chain kinase as the Ca2+-dependent modulator protein.
Myosin light chain kinase which phosphorylates g2 light chain of skeletal muscle myosin requires an activator for the activity… 
Highly Cited
1971
Highly Cited
1971
Paramyosin and the filaments of molluscan "catch" muscles. II. Native filaments: isolation and characterization.
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