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MutSalpha complex

Known as: MSH2/MSH6 complex, MSH2/MSH6 complex location, MutSalpha complex location 
A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
[A Case of Cecal Cancer Associated with Preoperatively Diagnosed Lynch Syndrome Caused by EPCAM Deletion].
A 43-year-old woman underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy for endometrioid adenocarcinoma of… Expand
Highly Cited
2009
Highly Cited
2009
Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway*
At clinically relevant doses, chemotherapeutic SN1 DNA methylating agents induce an ATR-mediated checkpoint response in human… Expand
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2006
2006
Analysis of the human MutLalpha.MutSalpha complex.
Human DNA mismatch repair is initiated by MutSalpha which ATP-dependently recruits MutLalpha. Analysis of this complex is… Expand
Highly Cited
2002
Highly Cited
2002
Phosphorylation of mismatch repair proteins MSH2 and MSH6 affecting MutSalpha mismatch-binding activity.
Mismatch repair (MMR) is involved in the removal of mispaired bases from DNA and thus plays an important role in the maintenance… Expand
Highly Cited
2001
Highly Cited
2001
A novel protein complex distinct from mismatch repair binds thioguanylated DNA.
To elucidate molecular mechanism(s) of cellular response to mercaptopurine, a widely used antileukemic agent, we assessed… Expand
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