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MutSalpha complex

Known as: MSH2/MSH6 complex, MSH2/MSH6 complex location, MutSalpha complex location 
A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two… Expand
National Institutes of Health

Papers overview

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2018
2018
[A Case of Cecal Cancer Associated with Preoperatively Diagnosed Lynch Syndrome Caused by EPCAM Deletion].
A 43-year-old woman underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy for endometrioid adenocarcinoma of… Expand
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2010
2010
Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway*
At clinically relevant doses, chemotherapeutic S(N)1 DNA methylating agents induce an ATR-mediated checkpoint response in human… Expand
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2006
2006
Analysis of the human MutLalpha.MutSalpha complex.
Human DNA mismatch repair is initiated by MutSalpha which ATP-dependently recruits MutLalpha. Analysis of this complex is… Expand
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2002
2002
Phosphorylation of mismatch repair proteins MSH2 and MSH6 affecting MutSalpha mismatch-binding activity.
Mismatch repair (MMR) is involved in the removal of mispaired bases from DNA and thus plays an important role in the maintenance… Expand
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2001
2001
A novel protein complex distinct from mismatch repair binds thioguanylated DNA.
To elucidate molecular mechanism(s) of cellular response to mercaptopurine, a widely used antileukemic agent, we assessed… Expand
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