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MutSalpha complex
Known as:
MSH2/MSH6 complex
, MSH2/MSH6 complex location
, MutSalpha complex location
A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two…
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
[A Case of Cecal Cancer Associated with Preoperatively Diagnosed Lynch Syndrome Caused by EPCAM Deletion].
A. Yamamoto
,
H. Eguchi
,
+10 authors
H. Ishida
Gan to kagaku ryoho. Cancer & chemotherapy
2018
Corpus ID: 59339296
A 43-year-old woman underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy for endometrioid adenocarcinoma of…
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Highly Cited
2009
Highly Cited
2009
Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway*
Yiyong Liu
,
Yanan Fang
,
Hongbing Shao
,
L. Lindsey-Boltz
,
A. Sancar
,
P. Modrich
Journal of Biological Chemistry
2009
Corpus ID: 25819828
At clinically relevant doses, chemotherapeutic SN1 DNA methylating agents induce an ATR-mediated checkpoint response in human…
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2006
2006
Analysis of the human MutLalpha.MutSalpha complex.
G. Plotz
,
A. Piiper
,
Marc Wormek
,
S. Zeuzem
,
J. Raedle
Biochemical and Biophysical Research…
2006
Corpus ID: 6703491
Human DNA mismatch repair is initiated by MutSalpha which ATP-dependently recruits MutLalpha. Analysis of this complex is…
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Highly Cited
2002
Highly Cited
2002
Phosphorylation of mismatch repair proteins MSH2 and MSH6 affecting MutSalpha mismatch-binding activity.
M. Christmann
,
M. Tomicic
,
B. Kaina
Nucleic Acids Research
2002
Corpus ID: 38888974
Mismatch repair (MMR) is involved in the removal of mispaired bases from DNA and thus plays an important role in the maintenance…
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Highly Cited
2001
Highly Cited
2001
A novel protein complex distinct from mismatch repair binds thioguanylated DNA.
E. Krynetski
,
N. Krynetskaia
,
A. Gallo
,
K. Murti
,
W. Evans
Molecular Pharmacology
2001
Corpus ID: 19497482
To elucidate molecular mechanism(s) of cellular response to mercaptopurine, a widely used antileukemic agent, we assessed…
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