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Muscular Dystrophy, Duchenne

Known as: Cardiomyopathy, Dilated, X-Linked, x-linked muscular dystrophy, Pseudohypertrophic Childhood Muscular Dystrophy 
An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the… 
National Institutes of Health

Related topics

Related topics

23 relations
Becker Muscular DystrophyCardiomyopathy, DilatedCongestive heart failureConnective and Soft Tissue

Broader (2)

Duchenne and Becker Muscular DystrophyMuscular Dystrophy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy
Gene replacement therapies utilizing adeno-associated viral (AAV) vectors hold great promise for treating Duchenne muscular… 
Highly Cited
2011
Highly Cited
2011
Interleukin-10 reduces the pathology of mdx muscular dystrophy by deactivating M1 macrophages and modulating macrophage phenotype.
M1 macrophages play a major role in worsening muscle injury in the mdx mouse model of Duchenne muscular dystrophy. However, mdx… 
Highly Cited
2010
Highly Cited
2010
Short Telomeres and Stem Cell Exhaustion Model Duchenne Muscular Dystrophy in mdx/mTR Mice
Highly Cited
2008
Highly Cited
2008
Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy
Muscular dystrophies comprise a diverse group of genetic disorders that lead to muscle wasting and, in many instances, premature… 
Highly Cited
2002
Highly Cited
2002
Modular flexibility of dystrophin: Implications for gene therapy of Duchenne muscular dystrophy
Attempts to develop gene therapy for Duchenne muscular dystrophy (DMD) have been complicated by the enormous size of the… 
Highly Cited
2002
Highly Cited
2002
Loss of myostatin attenuates severity of muscular dystrophy in mdx mice
Myostatin, a transforming growth factor–β family member, is a negative regulator of skeletal muscle growth. To explore the… 
Highly Cited
1990
Highly Cited
1990
Accelerated age-related decline in replicative life-span of Duchenne muscular dystrophy myoblasts: Implications for cell and gene therapy
An assessment of the replicative life-span of myoblasts is of fundamental importance in designing treatment strategies for… 
Highly Cited
1988
Highly Cited
1988
Muscular coactivation
The objective of this study was to quantify the coacti vation patterns of the knee flexor and extensor muscles as part of… 
Review
1984
Review
1984
Mechanisms of exercise-induced delayed onset muscular soreness: a brief review.
ABSTRACTARMSTRONG, R.B. Mechanisms of exercise-induced delayed onset muscular soreness: a brief review. Med. Sci. Sports Exerc… 
Highly Cited
1981
Highly Cited
1981
Critical power as a measure of physical work capacity and anaerobic threshold.
Monod and Scherrer (1965) showed that there was a linear relation between the maximal work and the maximal time over which the… 
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