FAQ

Muscular Dystrophy, Duchenne

Known as: Cardiomyopathy, Dilated, X-Linked, x-linked muscular dystrophy, Pseudohypertrophic Childhood Muscular Dystrophy 
An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1936-2017
0500100019362016

Related topics

Related topics

23 relations
Aspects of mortality statisticsBecker Muscular DystrophyCardiomyopathy, DilatedCongestive heart failure
(More)

Broader (2)

Duchenne and Becker Muscular DystrophyMuscular Dystrophy

Related mentions per year

Related mentions per year

1936-2019
19401960198020002020
Muscular Dystrophy, Duchenne
soft tissue
Skeletal bone
Weakness
Cardiomyopathy, Dilated
Muscular Dystrophy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Laminin-α2 Chain-Deficient Congenital Muscular Dystrophy: Pathophysiology and Development of Treatment.
Laminin-211 is a major constituent of the skeletal muscle basement membrane. It stabilizes skeletal muscle and influences signal… (More)
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Highly Cited
2011
Highly Cited
2011
Systemic administration of PRO051 in Duchenne's muscular dystrophy.
BACKGROUND Local intramuscular administration of the antisense oligonucleotide PRO051 in patients with Duchenne's muscular… (More)
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Highly Cited
2011
Highly Cited
2011
Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study
BACKGROUND We report clinical safety and biochemical efficacy from a dose-ranging study of intravenously administered AVI-4658… (More)
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Highly Cited
2010
Highly Cited
2010
Dystrophin immunity in Duchenne's muscular dystrophy.
We report on delivery of a functional dystrophin transgene to skeletal muscle in six patients with Duchenne's muscular dystrophy… (More)
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Highly Cited
1995
Highly Cited
1995
Myoblast transfer in the treatment of Duchenne's muscular dystrophy.
BACKGROUND Myoblast transfer has been proposed as a technique to replace dystrophin, the skeletal-muscle protein that is… (More)
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Highly Cited
1995
Highly Cited
1995
Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy
Nitric oxide (NO) is synthesized in skeletal muscle by neuronal-type NO synthase (nNOS), which is localized to sarcolemma of fast… (More)
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Highly Cited
1991
Highly Cited
1991
The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy
ALTHOUGH murine X-linked muscular dystrophy (mdx) and Duchenne muscular dystrophy (DMD) are genetically homologous and both… (More)
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Highly Cited
1988
Highly Cited
1988
Deletion screening of the Duchenne muscular dystrophy locus via multiplex DNA amplification.
The application of recombinant DNA technology to prenatal diagnosis of many recessively inherited X-linked diseases is… (More)
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Highly Cited
1987
Highly Cited
1987
Dystrophin: the protein product of the Duchenne muscular dystrophy locus.
The protein product of the human Duchenne muscular dystrophy locus (DMD) and its mouse homolog (mDMD) have been identified by… (More)
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Highly Cited
1987
Highly Cited
1987
Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals.
The 14 kb human Duchenne muscular dystrophy (DMD) cDNA corresponding to a complete representation of the fetal skeletal muscle… (More)
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