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The focus of this review is to provide an overview of the current state of knowledge of molecular mechanisms/processes that… Expand Vascular calcification is a common finding in atherosclerosis and a serious problem in diabetic and uremic patients. Because of… Expand Development of a vascular system involves the assembly of two principal cell types - endothelial cells and vascular smooth muscle… Expand The vascular smooth muscle cell (SMC) in mature animals is a highly specialized cell whose principal function is contraction. The… Expand The signaling pathways involved in the long-term metabolic effects of angiotensin II (Ang II) in vascular smooth muscle cells are… Expand NITRIC oxide is the major endothelium-derived relaxing factor (EDRF)1–3, and it is thought to relax smooth muscle cells by… Expand Endothelium-derived relaxing factor has been recently identified as nitric oxide. The purpose of this study was to determine if… Expand Despite its very potent vasodilating action in vivo, acetylcholine (ACh) does not always produce relaxation of isolated… Expand The essential connection of the basic physiological processes of excitation and contraction with transmembrane movements of Na, K… Expand