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Multifactor Dimensionality Reduction

Known as: Multifactor Dimensionality Reductions 
A statistical tool for detecting and modeling gene-gene interactions. It is a non-parametric and model-free approach.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2018
0102020032018

Related topics

Related topics

3 relations
legislation & jurisprudencestandards characteristicsstatistics & numerical data

Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
Multifactor Dimensionality Reduction
standards characteristics
legislation & jurisprudence
statistics & numerical data

Papers overview

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2011
2011
An R package implementation of multifactor dimensionality reduction
A breadth of high-dimensional data is now available with unprecedented numbers of genetic markers and data-mining approaches to… (More)
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2011
2011
Model-based multifactor dimensionality reduction for detecting epistasis in case-control data in the presence of noise.
Analyzing the combined effects of genes and/or environmental factors on the development of complex diseases is a great challenge… (More)
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2010
2010
FAM-MDR: A Flexible Family-Based Multifactor Dimensionality Reduction Technique to Detect Epistasis Using Related Individuals
We propose a novel multifactor dimensionality reduction method for epistasis detection in small or extended pedigrees, FAM-MDR… (More)
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2010
2010
cuGWAM: Genome-wide association multifactor dimensionality reduction using CUDA-enabled high-performance graphics processing unit
Multifactor dimensionality reduction (MDR) method has been widely applied to detect gene-gene interactions that are well… (More)
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2009
2009
A computationally efficient hypothesis testing method for epistasis analysis using multifactor dimensionality reduction.
Multifactor dimensionality reduction (MDR) was developed as a nonparametric and model-free data mining method for detecting… (More)
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2008
2008
MB-MDR: Model-Based Multifactor Dimensionality Reduction for detecting interactions in high-dimensional genomic data
Analyzing the effects of genes and environmental factors on the development of complex diseases is a great challenge from both… (More)
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2007
2007
Alternative contingency table measures improve the power and detection of multifactor dimensionality reduction
Multifactor Dimensionality Reduction (MDR) has been introduced previously as a non-parametric statistical method for detecting… (More)
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2007
2007
Log-linear model-based multifactor dimensionality reduction method to detect gene-gene interactions
MOTIVATION The identification and characterization of susceptibility genes that influence the risk of common and complex diseases… (More)
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2006
2006
Multifactor dimensionality reduction reveals gene–gene interactions associated with multiple sclerosis susceptibility in African Americans
Multiple sclerosis (MS) is a common disease of the central nervous system characterized by inflammation, myelin loss, gliosis… (More)
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Highly Cited
2003
Highly Cited
2003
Power of multifactor dimensionality reduction for detecting gene-gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity.
The identification and characterization of genes that influence the risk of common, complex multifactorial diseases, primarily… (More)
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