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Multidrug Resistance Modulator

Known as: Multidrug-Resistance Antagonists, Multidrug-Resistance Chemo Sensitizers, Chemosensitizer 
A drug that makes tumor cells more sensitive to the effects of chemotherapy.
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Src tyrosine kinase has been found to be overexpressed in both mouse and human ovarian cancer cells as well as in human primary… 
Highly Cited
2004
Highly Cited
2004
Overexpression of P-glycoprotein, encoded by the MDR1 gene, confers multidrug resistance (MDR) on cancer cells and is a frequent… 
Review
2004
Review
2004
The ability of malignant cells to develop resistance to chemotherapeutic drugs is a major obstacle to the successful treatment of… 
Highly Cited
2000
Highly Cited
2000
BACKGROUND Over-expression of the membrane glycoprotein called P-glycoprotein has been widely observed in a variety of both… 
Highly Cited
1996
Highly Cited
1996
Retroviral transfer of the multidrug-resistance 1 (mdr1) cDNA into primary human hematopoietic progenitor cells (HPC) of cancer… 
Highly Cited
1995
Highly Cited
1995
PURPOSE Dexverapamil is a competitive inhibitor of the P-glycoprotein (Pgp) efflux pump, a potent mechanism of multidrug… 
Review
1990
Review
1990
Multidrug resistance in animal cells is defined as the simultaneous resistance to a variety of compounds which appear to be…