Mullerian duct inhibiting substance

Known as: mullerian duct inhibiting substance (MIS), Mullerian-Inhibiting Factor, Mullerian Inhibiting Substance 
Muellerian-inhibiting factor (560 aa, ~59 kDa) is encoded by the human AMH gene. This protein plays a role in the development of the male… (More)
National Institutes of Health

Related topics

Related topics

15 relations
AMH geneAnti-Mullerian Hormone MeasurementCell Differentiation processCell Proliferation Regulatory Process
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Broader (3)

mullerian-inhibiting hormonepeptide hormonereproductive hormone

Papers overview

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Highly Cited
2005
Highly Cited
2005
Characterization and expression pattern of zebrafish Anti-Müllerian hormone (Amh) relative to sox9a, sox9b, and cyp19a1a, during gonad development.
The role of Anti-Müllerian hormone (Amh) during gonad development has been studied extensively in mammals, but is less well… (More)
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Highly Cited
2004
Highly Cited
2004
Serum antimüllerian hormone/müllerian-inhibiting substance appears to be a more discriminatory marker of assisted reproductive technology outcome than follicle-stimulating hormone, inhibin B, or…
OBJECTIVE To test the hypothesis that the concentration of early follicular phase serum antimullerian hormone (AMH) or mullerian… (More)
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Highly Cited
2002
Highly Cited
2002
SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7.
Small molecule inhibitors have proven extremely useful for investigating signal transduction pathways and have the potential for… (More)
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Highly Cited
1995
Highly Cited
1995
Anti-müllerian hormone and anti-müllerian hormone type II receptor messenger ribonucleic acid expression in rat ovaries during postnatal development, the estrous cycle, and gonadotropin-induced…
During fetal development, anti-müllerian hormone (AMH) is produced only by Sertoli cells, but postnatally, granulosa cells also… (More)
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Highly Cited
1995
Highly Cited
1995
Insensitivity to anti–Müllerian hormone due to a mutation in the human anti–Müllerian hormone receptor
Anti–Müllerian hormone (AMH) and its receptor are involved in the regression of Müllerian ducts in male fetuses. We have now… (More)
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Highly Cited
1994
Highly Cited
1994
Nuclear receptor steroidogenic factor 1 regulates the müllerian inhibiting substance gene: A link to the sex determination cascade
Normal male sex differentiation requires that Sertoli cells in the embryonic testes produce müllerian inhibiting substance (MIS… (More)
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Highly Cited
1991
Highly Cited
1991
Expression of the mouse anti-müllerian hormone gene suggests a role in both male and female sexual differentiation.
We describe here the isolation of cDNA and genomic clones corresponding to the mouse gene encoding anti-Müllerian hormone, and… (More)
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Highly Cited
1990
Highly Cited
1990
Abnormal sexual development in transgenic mice chronically expressing Müllerian inhibiting substance
MÜLLERIAN inhibiting substance (MIS), also known as anti-Müllerian hormone, is a glycoprotein1–4 normally secreted by the Sertoli… (More)
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Highly Cited
1987
Highly Cited
1987
A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family
The decapentaplegic gene complex (DPP-C) has been implicated in several events in pattern formation during Drosophila… (More)
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Highly Cited
1986
Highly Cited
1986
Isolation of the bovine and human genes for müllerian inhibiting substance and expression of the human gene in animal cells
We have isolated the bovine and human genes for Müllerian inhibiting substance (MIS), a testicular glycoprotein that causes… (More)
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