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Mucosal-Associated Invariant T-Cell
Known as:
Cell, MAIT
, MAIT Cell
, Cells, MAIT
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A T-cell subtype bearing a semi-invariant T-cell receptor and restricted by the major histocompatibility complex related molecule MR1. These cells…
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National Institutes of Health
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Related topics
Related topics
6 relations
Hematopoietic and Lymphoid Tissue
Lymphoid Tissue
Microbiological
Process of secretion
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Mucosal-Associated Invariant T Cells in Inflammatory Bowel Diseases: Bystanders, Defenders, or Offenders?
E. Treiner
Frontiers in Immunology
2015
Corpus ID: 2003587
The quest for new therapeutics and better follow-up of patients with inflammatory bowel diseases (IBD) requires the clearest…
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2011
2011
α-Galactosylceramide–Induced Airway Eosinophilia Is Mediated through the Activation of NKT Cells
Y. Chuang
,
Tzu-Chun Wang
,
Hsiao-Yu Jen
,
A. Yu
,
B. Chiang
Journal of Immunology
2011
Corpus ID: 39420406
Invariant NKT (iNKT) cells bridge innate and adaptive immune responses, resulting in the expansion of Ag-specific B and T cell…
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Highly Cited
2010
Highly Cited
2010
iNKT Cells Control Mouse Spontaneous Carcinoma Independently of Tumor-Specific Cytotoxic T Cells
M. Bellone
,
M. Ceccon
,
+6 authors
P. Dellabona
PLoS ONE
2010
Corpus ID: 14914402
Background CD1d-restricted invariant NKT (iNKT) cells are a subset of T lymphocytes endowed with innate effector functions that…
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Review
2010
Review
2010
Bacteria, mucosal‐associated invariant T cells and MR1
Wei-Jen Chua
,
T. Hansen
Immunology and Cell Biology
2010
Corpus ID: 27717815
Certain subpopulations of T lymphoctyes show innate-like properties that distinguish them from conventional T cells and thus have…
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Highly Cited
2009
Highly Cited
2009
Selective Requirement for c-Myc at an Early Stage of Vα14i NKT Cell Development 1
M. Mycko
,
I. Ferrero
,
+5 authors
H. Macdonald
Journal of Immunology
2009
Corpus ID: 24071923
Vα14 invariant (Vα14i) NKT cells are a subset of regulatory T cells that utilize a semi-invariant TCR to recognize glycolipids…
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2009
2009
Invariant TCR Rather Than CD1d Shapes the Preferential Activities of C-Glycoside Analogues Against Human Versus Murine Invariant NKT Cells1
Xiangming Li
,
T. Shiratsuchi
,
+4 authors
M. Tsuji
Journal of Immunology
2009
Corpus ID: 42876407
C-glycoside analogues of α-galactosylceramide were shown to activate both human and mouse invariant NKT (iNKT) cells. Among these…
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Highly Cited
2007
Highly Cited
2007
Invariant NKT Cells Biased for IL-5 Production Act as Crucial Regulators of Inflammation1
K. Sakuishi
,
S. Oki
,
M. Araki
,
S. Porcelli
,
S. Miyake
,
T. Yamamura
Journal of Immunology
2007
Corpus ID: 28740464
Although invariant NKT (iNKT) cells play a regulatory role in the pathogenesis of autoimmune diseases and allergy, an initial…
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2007
2007
The Pro-Th1 Cytokine IL-12 Enhances IL-4 Production by Invariant NKT Cells: Relevance for T Cell-Mediated Hepatitis1
R. Zhu
,
Séverine Diem
,
+9 authors
A. Herbelin
Journal of Immunology
2007
Corpus ID: 23570983
IL-12 is essential for invariant NKT (iNKT) cells because it can maintain a functionally active population and promote a cytokine…
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2007
2007
Subcongenic analysis of genetic basis for impaired development of invariant NKT cells in NOD mice
Yi-Guang Chen
,
J. Driver
,
P. Silveira
,
D. Serreze
Immunogenetics
2007
Corpus ID: 23725056
Reduced numbers and function of invariant NKT (iNKT) cells partially contribute to type 1 diabetes (T1D) development in NOD mice…
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Highly Cited
2003
Highly Cited
2003
Structural Features of the Acyl Chain Determine Self-phospholipid Antigen Recognition by a CD1d-restricted Invariant NKT (iNKT) Cell*
J. Rauch
,
J. Gumperz
,
+8 authors
S. Behar
Journal of Biological Chemistry
2003
Corpus ID: 19354538
Little is known about the antigen specificity of CD1d-restricted T cells, except that they frequently recognize CD1d-expressing…
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