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Mucosal-Associated Invariant T-Cell

Known as: Cell, MAIT, MAIT Cell, Cells, MAIT 
A T-cell subtype bearing a semi-invariant T-cell receptor and restricted by the major histocompatibility complex related molecule MR1. These cells… 
National Institutes of Health

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6 relations
Hematopoietic and Lymphoid TissueLymphoid TissueMicrobiologicalProcess of secretion

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Ontogeny of human mucosal-associated invariant T cells and related T cell subsets
Mucosal-associated invariant T (MAIT) cells are semi-invariant V&agr;7.2+ CD161highCD4− T cells that recognize microbial… 
Highly Cited
2016
Highly Cited
2016
Involvement of Mucosal-associated Invariant T cells in Ankylosing Spondylitis
Objective. Ankylosing spondylitis (AS) is characterized by chronic inflammation of the axial and peripheral joints and… 
Review
2016
Review
2016
Mucosal‐associated invariant T cells in autoimmunity, immune‐mediated diseases and airways disease
Mucosal‐associated invariant T (MAIT) cells are a novel class of innate‐like T cells, expressing a semi‐invariant T‐cell receptor… 
Highly Cited
2015
Highly Cited
2015
Mucosal-associated invariant T cell-rich congenic mouse strain allows functional evaluation.
Mucosal-associated invariant T cells (MAITs) have potent antimicrobial activity and are abundant in humans (5%-10% in blood… 
Highly Cited
2015
Highly Cited
2015
Mucosal-Associated Invariant T Cells in the Human Gastric Mucosa and Blood: Role in Helicobacter pylori Infection
Mucosal-associated invariant T (MAIT) cells represent a class of antimicrobial innate-like T cells that have been characterized… 
Review
2015
Review
2015
MR1-Restricted Mucosal-Associated Invariant T Cells and Their Activation during Infectious Diseases
MR1-restricted mucosal-associated invariant T (MAIT) cells recognize vitamin B metabolites, which are generated by a broad range… 
Review
2011
Review
2011
Mucosal-associated invariant T cells: unconventional development and function.
Highly Cited
2007
Highly Cited
2007
Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency
CD1d-restricted natural killer T (NKT) cells, expressing the invariant T cell antigen receptor (TCR) chain encoded by Vα14-Jα18… 
Highly Cited
2007
Highly Cited
2007
Type II NKT cell-mediated anergy induction in type I NKT cells prevents inflammatory liver disease.
Because of the paucity of known self lipid-reactive ligands for NKT cells, interactions among distinct NKT cell subsets as well… 
Highly Cited
2003
Highly Cited
2003
Cutting Edge: Invariant Vα14 NKT Cells Are Required for Allergen-Induced Airway Inflammation and Hyperreactivity in an Experimental Asthma Model1
Airway hyperreactivity (AHR), eosinophilic inflammation with a Th2-type cytokine profile, and specific Th2-mediated IgE… 
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