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Mouse mammary tumor virus

Known as: milk agent, MMTV, Mammary Tumor Viruses, Mouse 
Type B retrovirus. Etiologic agent of mouse mammary tumors. Transmitted horizontally through the lactating mammary gland and vertically through the… 
National Institutes of Health

Related topics

Related topics

9 relations

Broader (3)

BetaretrovirusRetroviridaeRetroviruses Type B, Mammalian
Minor Lymphocyte Stimulatory AntigensMinor Lymphocyte Stimulatory Lociaspects of radiation effectsmammary tumor virus

Narrower (1)

murine nodule inducing virus

Papers overview

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Highly Cited
2010
Highly Cited
2010
RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis
RANK ligand (RANKL), a TNF-related molecule, is essential for osteoclast formation, function and survival through interaction… 
Highly Cited
2002
Highly Cited
2002
Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects.
TGF-betas play diverse and complex roles in many biological processes. In tumorigenesis, they can function either as tumor… 
Highly Cited
2001
Highly Cited
2001
Transgenic MUC1 Interacts with Epidermal Growth Factor Receptor and Correlates with Mitogen-activated Protein Kinase Activation in the Mouse Mammary Gland*
MUC1 is a large (>400 kDa), heavily glycosylated transmembrane protein that is aberrantly expressed on greater than 90% of human… 
Highly Cited
1998
Highly Cited
1998
An entire functional mammary gland may comprise the progeny from a single cell.
Any epithelial portion of a normal mouse mammary gland can reproduce an entire functional gland when transplanted into an… 
Highly Cited
1996
Highly Cited
1996
Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene.
The int-3 oncogene was identified as a frequent target in Mouse Mammary Tumor Virus (MMTV)-induced mammary carcinomas and encodes… 
Review
1993
Review
1993
Superantigens and their potential role in human disease.
Highly Cited
1992
Highly Cited
1992
Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells
Expression of a 2.3-kb RNA species is induced in mammary tumors as a consequence of insertional mutagenesis at the int-3 locus by… 
Highly Cited
1989
Highly Cited
1989
Stochastic appearance of mammary tumors in transgenic mice carrying the MMTV/c-neu oncogene
Highly Cited
1988
Highly Cited
1988
Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice
Highly Cited
1983
Highly Cited
1983
The glucocorticoid receptor binds to defined nucleotide sequences near the promoter of mouse mammary tumour virus
Glucocorticoids are known to induce the transcription of integrated proviral mouse mammary tumour virus (MMTV) genes in a variety… 
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