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Monosomy 5

A cytogenetic aneuploidy abnormality that refers to the presence of one chromosome 5 only. It is associated with the development of refractory anemia… 
National Institutes of Health

Related topics

Related topics

7 relations
Chromosomes, Human, Pair 5RAEB with FibrosisRAEB-1RAEB-2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Independent Prognostic Significance of Monosomy 17 and Impact of Karyotype Complexity in Monosomal Karyotype/Complex Karyotype Acute Myeloid Leukemia: Results from Four ECOG-ACRIN Prospective…
Highly Cited
2010
Highly Cited
2010
Monosomal karyotype in myelodysplastic syndromes, with or without monosomy 7 or 5, is prognostically worse than an otherwise complex karyotype
Monosomal karyotype (MK) refers to the presence of two or more distinct autosomal monosomies or a single monosomy associated with… 
2009
2009
The heterogeneous prognosis of patients with myelodysplastic syndrome and chromosome 5 abnormalities
To define the prognosis in myelodysplastic syndrome (MDS) and deletion 5q with or without other cytogenetic abnormalities. 
2007
2007
Redefining monosomy 5 by molecular cytogenetics in 23 patients with MDS/AML
Deletion of the long arm of chromosome 5 [del(5q)] or loss of a whole chromosome 5 (−5) is a common finding, arising de novo in… 
Highly Cited
2006
Highly Cited
2006
Clofarabine and cytarabine combination as induction therapy for acute myeloid leukemia (AML) in patients 50 years of age or older.
Outcome of patients with acute myeloid leukemia (AML) who are older than 60 years of age remains unsatisfactory, with low… 
2001
2001
Further characterization of complex chromosomal rearrangements in myeloid malignancies: spectral karyotyping adds precision in defining abnormalities associated with poor prognosis
Further characterization of complex chromosomal rearrangements in myeloid malignancies: spectral karyotyping adds precision in… 
Review
1999
Review
1999
Myelodysplastic syndrome with monosomy 5 and/or 7 following therapy with 2‐chloro‐2′‐deoxyadenosine
A few cases of secondary neoplasms occurring after treatment with 2‐chloro‐2′‐deoxyadenosine (2CdA) have been reported, mostly in… 
1995
1995
Association of rat p15INK4B/p16INK4 deletions with monosomy 5 in kidney epithelial cell lines but not primary renal tumors.
Recently the putative tumor suppressor gene p16INK4 was mapped to human chromosome 9p21, which is homologous to rat chromosome 5… 
Review
1989
Review
1989
Occupational history and involvement of chromosomes 5 and 7 in acute nonlymphocytic leukemia.
Highly Cited
1983
Highly Cited
1983
Nonrandom cytogenetic changes in New Zealand patients with acute myeloid leukemia.
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