Molecular Diagnosis

The process of identifying a disease by studying molecules, such as proteins, DNA, and RNA, in a tissue or fluid.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2018
05010019732018

Papers overview

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Highly Cited
2014
Highly Cited
2014
IMPORTANCE Clinical whole-exome sequencing is increasingly used for diagnostic evaluation of patients with suspected genetic… (More)
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Highly Cited
2013
Highly Cited
2013
OBJECTIVE Our objective was to evaluate the levels of miR-210 in tumor and serum samples of conventional renal cell cancer (cRCC… (More)
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Highly Cited
2012
Highly Cited
2012
Assessing the impact of variants of unknown significance (VUS) on splicing is a key issue in molecular diagnosis. This impact can… (More)
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Highly Cited
2010
Highly Cited
2010
MicroRNA (miRNA) opens up a new field for molecular diagnosis of cancer. However, the role of circulating miRNAs in plasma/serum… (More)
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Highly Cited
2007
Highly Cited
2007
Owing to its cross-linking effects, it is currently believed that formalin fixation of routinely processed tissues in the clinic… (More)
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Highly Cited
2005
Highly Cited
2005
Recurrent chromosomal rearrangements have not been well characterized in common carcinomas. We used a bioinformatics approach to… (More)
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Highly Cited
2003
Highly Cited
2003
Using current diagnostic criteria, primary mediastinal B cell lymphoma (PMBL) cannot be distinguished from other types of diffuse… (More)
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Highly Cited
2003
Highly Cited
2003
We used gene expression profiling to establish a molecular diagnosis of mantle cell lymphoma (MCL), to elucidate its pathogenesis… (More)
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Highly Cited
2001
Highly Cited
2001
  • P Cairns, M Esteller, +8 authors David Sidransky
  • Clinical cancer research : an official journal of…
  • 2001
Novel approaches for the early detection and management of prostate cancer are urgently needed. Clonal genetic alterations have… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The potential use of plasma and serum for molecular diagnosis has generated interest. Tumour DNA has been found in… (More)
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