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Mismatch Probe

A 25 nucleotide probe with a sequence mismatch to its target at position 13 used for measuring non-specific binding in analysis of Affymetrix arrays.
National Institutes of Health

Papers overview

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2010
2010
Designed thiazole orange nucleotides for the synthesis of single labelled oligonucleotides that fluoresce upon matched hybridization.
Probe molecules that enable the detection of specific DNA sequences are used in diagnostic and basic research. Most methods rely… 
2010
2010
Molecular Imaging of MDM2 Messenger RNA with 99mTc-Labeled Antisense Oligonucleotides in Experimental Human Breast Cancer Xenografts
The mouse double-minute 2 (MDM2) oncogene, amplified or overexpressed in many human cancers, has been suggested to be a novel… 
2009
2009
Physico-chemical modelling of target depletion during hybridization on oligonulceotide microarrays
The effect of target molecule depletion from the supernatant solution is incorporated into a physico-chemical model of… 
2008
2008
Design and analysis of mismatch probes for long oligonucleotide microarrays
BackgroundNonspecific hybridization is currently a major concern with microarray technology. One of most effective approaches to… 
2008
2008
Effect of single nucleotide polymorphisms on Affymetrix® match-mismatch probe pairs
Microarrays provide a means of studying expression level of tens of thousands of genes by providing one or more oligonucleotide… 
Highly Cited
2007
Highly Cited
2007
Comparative High-Density Microarray Analysis of Gene Expression during Growth of Lactobacillus helveticus in Milk versus Rich Culture Medium
ABSTRACT Lactobacillus helveticus CNRZ32 is used by the dairy industry to modulate cheese flavor. The compilation of a draft… 
2007
2007
PET Imaging of CCND1 mRNA in Human MCF7 Estrogen Receptor–Positive Breast Cancer Xenografts with Oncogene-Specific [64Cu]Chelator-Peptide Nucleic Acid-IGF1 Analog Radiohybridization Probes
Treatment of breast cancer is hampered by a large unmet need for rapid, sensitive, specific staging and stratification of… 
2007
2007
PCR amplification on magnetic nanoparticles: Application for high‐throughput single nucleotide polymorphism genotyping
A novel approach for the genotyping of single nucleotide polymorphisms (SNPs) based on solidphase PCR on magnetic nanoparticles… 
2005
2005
From CEL Files to Annotated Lists of Interesting Genes
One of the most popular applications of microarray technology is the identification of genes that are differentially expressed in… 
Highly Cited
2002
Highly Cited
2002
A systematic statistical linear modeling approach to oligonucleotide array experiments.
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