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Mismatch Probe

A 25 nucleotide probe with a sequence mismatch to its target at position 13 used for measuring non-specific binding in analysis of Affymetrix arrays.
National Institutes of Health

Papers overview

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2010
2010
Designed thiazole orange nucleotides for the synthesis of single labelled oligonucleotides that fluoresce upon matched hybridization.
Probe molecules that enable the detection of specific DNA sequences are used in diagnostic and basic research. Most methods rely… Expand
2010
2010
articleDownregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFδ / δ mouse model of amyotrophic lateral sclerosis
Background: Vascular endothelial growth factor (VEGF) is an endothelial cell mitogen that stimulates vasculogenesis. It has also… Expand
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2008
2008
Effect of single nucleotide polymorphisms on Affymetrix® match-mismatch probe pairs
Microarrays provide a means of studying expression level of tens of thousands of genes by providing one or more oligonucleotide… Expand
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2008
2008
Design and analysis of mismatch probes for long oligonucleotide microarrays
BackgroundNonspecific hybridization is currently a major concern with microarray technology. One of most effective approaches to… Expand
Highly Cited
2007
Highly Cited
2007
Comparative High-Density Microarray Analysis of Gene Expression during Growth of Lactobacillus helveticus in Milk versus Rich Culture Medium
ABSTRACT Lactobacillus helveticus CNRZ32 is used by the dairy industry to modulate cheese flavor. The compilation of a draft… Expand
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2007
2007
PET Imaging of CCND1 mRNA in Human MCF7 Estrogen Receptor–Positive Breast Cancer Xenografts with Oncogene-Specific [64Cu]Chelator-Peptide Nucleic Acid-IGF1 Analog Radiohybridization Probes
Treatment of breast cancer is hampered by a large unmet need for rapid, sensitive, specific staging and stratification of… Expand
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2007
2007
PCR amplification on magnetic nanoparticles: Application for high‐throughput single nucleotide polymorphism genotyping
A novel approach for the genotyping of single nucleotide polymorphisms (SNPs) based on solidphase PCR on magnetic nanoparticles… Expand
2005
2005
From CEL Files to Annotated Lists of Interesting Genes
One of the most popular applications of microarray technology is the identification of genes that are differentially expressed in… Expand
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2004
2004
SUM: a new way to incorporate mismatch probe measurements.
Affymetrix's high-density oligonucleotide arrays offer an exciting technology in biomedical research. With more and more… Expand
Highly Cited
2002
Highly Cited
2002
A systematic statistical linear modeling approach to oligonucleotide array experiments.
We outline and describe steps for a statistically rigorous approach to analyzing probe-level Affymetrix GeneChip data. The… Expand
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