Microvillus inclusion disease

ABSTRACT The intestinal epithelium is a highly organized tissue. The establishment of epithelial cell polarity, with distinct… Expand

The motor protein Myo5B and t-SNARE Stx3 drive cargo-selective apical exocytosis in polarized epithelial cells in a pathway… Expand

Inherited MYO5B mutations have recently been associated with microvillus inclusion disease (MVID), an autosomal recessive… Expand

Microvillus inclusion disease (MVID) is a disorder of intestinal epithelial differentiation characterized by life-threatening… Expand

Microvillus inclusion disease (MVID) is a severe form of congenital diarrhea that arises from inactivating mutations in the gene… Expand

Autosomal recessive microvillus inclusion disease (MVID) is characterized by an intractable diarrhea starting within the first… Expand

Following homozygosity mapping in a single kindred, we identified nonsense and missense mutations in MYO5B, encoding type Vb… Expand

The striking similarities between microvillus inclusions (MIs) in enterocytes in microvillus inclusion disease (MID) and vacuolar… Expand

A technique using alkaline phosphatase histochemistry on routine sections of four jejunal biopsy specimens and one necropsy… Expand

Thirty infants with intractable diarrhea of infancy (IDI) underwent small bowel biopsies in order to determine the extent and… Expand