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Microparticle MDP/Bacterial DNA-containing MIS416

Known as: MIS-416, MIS416, Microparticle MIS416 
A microparticle combining two immune-modifying components derived from the bacterium Propionibacterium acnes, a bacterial cell wall component that is… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
First-in-human phase I clinical trial of NY-ESO-1 protein cancer vaccine with a novel adjuvant MIS416, NOD2 and TLR9 stimulant, for patients with NY-ESO-1 expressing solid tumors.
e15176Background: Complexes of Cholesteryl pullulan and NY-ESO-1 antigen (CHP-NY-ESO-1) present multiple epitope peptides to both… 
Review
2017
Review
2017
’ s response to reviews Title : Evaluation of neurological changes in secondary progressive multiple sclerosis patients treated with immune modulator MIS 416 : Results from a Feasibility Study
Title: Evaluation of neurological changes in secondary progressive multiple sclerosis patients treated with immune modulator… 
2016
2016
Development of a new microparticle vaccine adjuvant, MIS416
MIS416 is a novel vaccine adjuvant generated from propionibacterium acnes cell wall skeletons comprising naturally occurring… 
2015
2015
Bridging Small Molecules to Modified Bacterial Microparticles Using a Disulphide Linkage: MIS416 as a Cargo Delivery System
MIS416 is an intact minimal cell wall skeleton derived from Proprionibacterium acnes that is phagocytosed by antigen presenting… 
2015
2015
Innate immunomodulation with MIS416: mechanism of action in experimental autoimmune encephalomyelitis
Multiple sclerosis (MS) is an immune-mediated disease in which self-reacting T lymphocytes enter the central nervous system (CNS… 
2014
2014
Innate cell modulator MIS416 suppresses CNS disease in EAE
2009
2009
Abstract #LB-159: MIS416: A second generation microparticle-based immune response modifier has broad spectrum anti-neoplastic activity in several pre-clinical mouse models
Immune response modifiers (IRM) are agents that target the body\#8217;s immune system to combat disease by the mobilization and… 
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