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Reactive astrocytes are strongly induced by central nervous system (CNS) injury and disease, but their role is poorly understood… Expand Microglia are the resident CNS immune cells and active surveyors of the extracellular environment. While past work has focused on… Expand Microglial cells are the resident macrophages in the central nervous system. These cells of mesodermal/mesenchymal origin migrate… Expand A good brain needs a good vacuum cleaner. Microglia are highly motile phagocytic cells that infiltrate and take up residence in… Expand Primitive Origins for Microglia Microglia are the resident macrophages of the central nervous system and are associated with… Expand Microglia, the resident macrophages of the CNS, are exquisitely sensitive to brain injury and disease, altering their morphology… Expand Mounting evidence indicates that microglial activation contributes to neuronal damage in neurodegenerative diseases. Recent… Expand Microglial cells constitute the resident macrophage population of the CNS. Recent in vivo studies have shown that microglia carry… Expand During the past decade, mechanisms involved in the immune surveillance of the central nervous system (CNS) have moved to the… Expand The most characteristic feature of microglial cells is their rapid activation in response to even minor pathological changes in… Expand