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Mice, Neurologic Mutants

Known as: Neurologic Mutant Mice, Mice, Neurologic Mutant, Neurological Mutant Mouse 
Mice which carry mutant genes for neurologic defects or abnormalities.
National Institutes of Health

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Chakragati MiceLurcher MiceReeler MiceStaggerer Mice
In BloodMicrobiologicalphysiological aspects

Papers overview

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Highly Cited
2017
Highly Cited
2017
Mutant IDH1 regulates the tumor-associated immune system in gliomas
Amankulor et al. created a syngeneic pair mouse model for mutant IDH1 (muIDH1) and wild-type IDH1 (wtIDH1) gliomas and… 
Highly Cited
2017
Highly Cited
2017
Sequential, Divergent, and Cooperative Requirements of Foxl2a and Foxl2b in Ovary Development and Maintenance of Zebrafish
Foxl2 is essential for mammalian ovary maintenance. Although sexually dimorphic expression of foxl2 was observed in many teleosts… 
Highly Cited
2014
Highly Cited
2014
Sulforaphane enhances proteasomal and autophagic activities in mice and is a potential therapeutic reagent for Huntington's disease
The ubiquitin proteasome system (UPS) is impaired in Huntington's disease, a devastating neurodegenerative disorder. Sulforaphane… 
Highly Cited
2012
Highly Cited
2012
Calpain and STriatal-Enriched protein tyrosine phosphatase (STEP) activation contribute to extrasynaptic NMDA receptor localization in a Huntington's disease mouse model.
In Huntington's disease (HD), the mutant huntingtin (mhtt) protein is associated with striatal dysfunction and degeneration… 
Highly Cited
2010
Highly Cited
2010
Early autophagic response in a novel knock-in model of Huntington disease.
The aggregation of mutant polyglutamine (polyQ) proteins has sparked interest in the role of protein quality-control pathways in… 
Highly Cited
2008
Highly Cited
2008
Thymidine kinase 2 (H126N) knockin mice show the essential role of balanced deoxynucleotide pools for mitochondrial DNA maintenance.
Mitochondrial DNA (mtDNA) depletion syndrome (MDS), an autosomal recessive condition, is characterized by variable organ… 
Highly Cited
2001
Highly Cited
2001
Nerve Growth Factor Stimulates Multisite Tyrosine Phosphorylation and Activation of the Atypical Protein Kinase C's via a src Kinase Pathway
ABSTRACT Atypical protein kinase C (PKC) isoforms are required for nerve growth factor (NGF)-initiated differentiation of PC12… 
Highly Cited
1999
Highly Cited
1999
Impaired cerebellar synapse maturation in waggler, a mutant mouse with a disrupted neuronal calcium channel gamma subunit.
The waggler, a neurological mutant mouse with a disrupted putative neuronal Ca(2+) channel gamma subunit, exhibits a cerebellar… 
Highly Cited
1998
Highly Cited
1998
West Nile virus envelope proteins: nucleotide sequence analysis of strains differing in mouse neuroinvasiveness.
Several neuroinvasive and non-neuroinvasive West Nile (WN) viruses were characterized by nucleotide sequencing of their envelope… 
Highly Cited
1991
Highly Cited
1991
Independent emergence of a vaccine-induced escape mutant of hepatitis B virus.
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