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Mice, Jimpy

Known as: Jimpy Mice 
Myelin-deficient mutants which are from the inbred Tabby-Jimpy strain.
National Institutes of Health

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3 relations
In BloodMicrobiologicalphysiological aspects

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Highly Cited
2006
Highly Cited
2006
Perturbed Interactions of Mutant Proteolipid Protein/DM20 with Cholesterol and Lipid Rafts in Oligodendroglia: Implications for Dysmyelination in Spastic Paraplegia
Missense mutations in the human PLP1 gene lead to dysmyelinating diseases with a broad range of clinical severity, ranging from… Expand
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1995
1995
Microglial cell reaction in the gray and white matter in spinal cords from jimpy mice. An enzyme histochemical study at the light and electron microscope level
Jimpy is a genetic disorder which results in a severe hypomyelination in the central nervous system associated with a variety of… Expand
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1991
1991
Developmental expression of glial fibrillary acidic protein and glutamine synthetase mRNAs in normal and jimpy mice.
  • X. Li, W. Bartlett
  • Brain research. Molecular brain research
  • 1991
    • Corpus ID: 39300975
Astrogliosis is a prominent feature in the CNS of the dysmyelinating mutant, jimpy. In the following study the expression of the… Expand
1988
1988
Astroglial plasticity in hemizygous and heterozygous jimpy mice
Gliosis is a common phenomenon which occurs in many human diseases and in experimentally altered nervous tissue. The factors… Expand
1983
1983
Axonal swellings in jimpy mice: Does lack of myelin cause neuronal abnormalities?
We have observed focal axonal enlargements in jimpy, a myelin deficient mutant mouse. Similar axonal swellings have also been… Expand
1980
1980
Immunohistochemical localization of the myelin basic protein and of the glial fibrillary acidic protein: Comparative study in normal, quaking and jimpy mice
The topographical distribution of myelin basic protein (MBP) and of glial fibrillary acidic protein (GFA) have been compared in… Expand
1978
1978
PLASMALOGENASE ACTIVITIES IN THE BRAINS OF JIMPY AND QUAKING MICE
The activity of plasmalogenase, which hydrolyzes the vinyl ether linkage of the plasmalogen molecule, increased markedly in… Expand
1977
1977
Arylsulfatase A in developing normal and jimpy mice
Abstract Total activity, pH optimum and heat inactivation of arylsulfatase A (EC 3.1.6.1) were followed during development in… Expand
1975
1975
Alpha hydroxylation of lignoceric acid to cerebronic acid during brain development. Diminished hydroxylase activity in myelin-deficient mouse mutants.
Alpha Hydroxylation of lignoceric acid (n-tetracosanoic acid) to cerebronic acid (2-hydroxylignoceric acid) by postnuclear… Expand
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1969
1969
HYDROLASE ACTIVITIES IN BRAIN OF NEUROLOGICAL MUTANTS: CEREBROSIDE GALACTOSIDASE, NITROPHENYL GALACTOSIDE HYDROLASE, NITROPHENYL LUCOSIDE HYDROLASE AND SULPHATASE 1
Abstract— 1 The brains of 17‐day‐old quaking and jimpy mice were compared with those of the corresponding normal phenotypes. The… Expand
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