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Mice, Inbred NZB

Known as: Mouse, Inbred NZB, NZB Mouse, Inbred, Mice, NZB 
An inbred strain of mouse that is widely used as a model for AUTOIMMUNE DISEASES such as SYSTEMIC LUPUS ERYTHEMATOSUS.
National Institutes of Health

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3 relations
In BloodMicrobiologicalphysiological aspects

Papers overview

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Highly Cited
1994
Highly Cited
1994
Polygenic control of susceptibility to murine systemic lupus erythematosus.
Highly Cited
1994
Highly Cited
1994
Lupus susceptibility loci in New Zealand mice.
Susceptibility to systemic lupus erythematosus has been unequivocally established to be an inherited trait, but the exact genes… 
Highly Cited
1987
Highly Cited
1987
In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon
The (NZB X NZW)F1 mouse is recognized as an important animal model of the human disease systemic lupus erythematosus (SLE… 
Highly Cited
1985
Highly Cited
1985
Successful treatment of autoimmunity in NZB/NZW F1 mice with monoclonal antibody to L3T4
Autoimmune NZB/NZW mice were treated with weekly injections of monoclonal antibody (mAb) to L3T4, an antigen expressed on a… 
Highly Cited
1985
Highly Cited
1985
NZB mouse system for production of monoclonal antibodies to weak bacterial antigens: isolation of an IgG antibody to the polysaccharide capsules of Escherichia coli K1 and group B meningococci.
A system for the production of monoclonal antibodies, particularly of the IgG type, against weakly immunogenic bacterial… 
Highly Cited
1984
Highly Cited
1984
Ly-1 B cells: functionally distinct lymphocytes that secrete IgM autoantibodies.
Studies presented here introduce another perspective on the mechanisms responsible for IgM autoantibody production. A unique… 
Highly Cited
1983
Highly Cited
1983
The "Ly-1 B" cell subpopulation in normal immunodefective, and autoimmune mice
A small subpopulation of normal murine splenic B cells carrying all of the classic B cells markers (IgM, IgD, Ia, and ThB) also… 
Highly Cited
1981
Highly Cited
1981
Dietary enrichment with the polyunsaturated fatty acid eicosapentaenoic acid prevents proteinuria and prolongs survival in NZB x NZW F1 mice.
Prostaglandins and related compounds are active mediators of inflammation, but data concerning their role in the pathogenesis of… 
Highly Cited
1978
Highly Cited
1978
Effect of castration and sex hormone treatment on survival, anti- nucleic acid antibodies, and glomerulonephritis in NZB/NZW F1 mice
NZB/NZW F1 mice of both sexes were castrated at 2 wk of age and implanted subcutaneously with silastic tubes containing either 5… 
Highly Cited
1978
Highly Cited
1978
Immunoregulatory circuits among T-cell sets. II. Physiologic role of feedback inhibition in vivo: absence in NZB mice
We have shown that (a) purified T-helper cells induce cells of another T-cell set-, expressing the Ly123+Qa1+ surface phenotype… 
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