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Mice, Inbred mdx

Known as: mdx Mouse, Inbred mdx Mice, Inbred mdx Mouse 
A strain of mice arising from a spontaneous MUTATION (mdx) in inbred C57BL mice. This mutation is X chromosome-linked and produces viable homozygous… 
National Institutes of Health

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DystrophinIn BloodMicrobiologicalMuscular Dystrophy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle
Accumulation of adipocytes and collagen type-I-producing cells (fibrosis) is observed in muscular dystrophies. The origin of… 
Highly Cited
2011
Highly Cited
2011
Interleukin-10 reduces the pathology of mdx muscular dystrophy by deactivating M1 macrophages and modulating macrophage phenotype.
M1 macrophages play a major role in worsening muscle injury in the mdx mouse model of Duchenne muscular dystrophy. However, mdx… 
Highly Cited
2008
Highly Cited
2008
Nanopolymers improve delivery of exon skipping oligonucleotides and concomitant dystrophin expression in skeletal muscle of mdx mice
BackgroundExon skipping oligonucleotides (ESOs) of 2'O-Methyl (2'OMe) and morpholino chemistry have been shown to restore… 
Highly Cited
2004
Highly Cited
2004
Evolution of the mdx mouse cardiomyopathy: physiological and morphological findings
Review
2002
Review
2002
Muscular dystrophies involving the dystrophin-glycoprotein complex: an overview of current mouse models.
Highly Cited
1995
Highly Cited
1995
Visualization of dystrophic muscle fibers in mdx mouse by vital staining with Evans blue: evidence of apoptosis in dystrophin-deficient muscle.
Degenerating muscle fibers in the skeletal muscle of mdx mice were visualized by vital staining with Evans blue. Evans blue… 
Highly Cited
1995
Highly Cited
1995
Apoptosis precedes necrosis of dystrophin-deficient muscle.
The current view that death of dystrophin-deficient muscle fibers is a necrotic process relies primarily upon the histological… 
Highly Cited
1991
Highly Cited
1991
Decreased osmotic stability of dystrophin-less muscle cells from the mdx mouse
HUMAN X-linked Duchenne and Becker muscular dystrophies are due to defects in dystrophin, the product of an exceptionally large… 
Highly Cited
1988
Highly Cited
1988
THE mdx MOUSE SKELETAL MUSCLE MYOPATHY: I. A HISTOLOGICAL, MORPHOMETRIC AND BIOCHEMICAL INVESTIGATION
Skeletal muscle has been examined in a colony of the mdx strain of myopathic mice. Sixty-five mice from 22 to 303 days of age… 
Highly Cited
1987
Highly Cited
1987
Muscular dystrophy in the mdx mouse: Histopathology of the soleus and extensor digitorum longus muscles
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