Dystrophin

Known as: Dystrophin [Chemical/Ingredient] 
A muscle protein localized in surface membranes which is the product of the Duchenne/Becker muscular dystrophy gene. Individuals with Duchenne… (More)
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
BACKGROUND Mutations that disrupt the open reading frame and prevent full translation of DMD, the gene that encodes dystrophin… (More)
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Highly Cited
1999
Highly Cited
1999
Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene, leading to the absence of the dystrophin protein… (More)
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Highly Cited
1997
Highly Cited
1997
The absence of dystrophin at the muscle membrane leads to Duchenne muscular dystrophy (DMD), a severe muscle-wasting disease that… (More)
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Highly Cited
1997
Highly Cited
1997
Dystrophin is a cytoskeletal protein of muscle fibers; its loss in humans leads to Duchenne muscular dystrophy, an inevitably… (More)
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Highly Cited
1995
Highly Cited
1995
Nitric oxide (NO) is synthesized in skeletal muscle by neuronal-type NO synthase (nNOS), which is localized to sarcolemma of fast… (More)
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Highly Cited
1995
Highly Cited
1995
We have directly measured the contribution of dystrophin to the cortical stiffness of living muscle cells and have demonstrated… (More)
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Highly Cited
1993
Highly Cited
1993
The protein dystrophin, normally found on the cytoplasmic surface of skeletal muscle cell membranes, is absent in patients with… (More)
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Highly Cited
1991
Highly Cited
1991
The stoichiometry, cellular location, glycosylation, and hydrophobic properties of the components in the dystrophin-glycoprotein… (More)
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Highly Cited
1989
Highly Cited
1989
An important corollary to the recent advances in our understanding of the primary cause of Duchenne muscular dystrophy1–6, is the… (More)
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Highly Cited
1989
Highly Cited
1989
DUCHENNE muscular dystrophy (DMD) is caused by a defective gene found on the X-chromosome1. Dystrophin is encoded by the DMD gene… (More)
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