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Mezlocillin

Known as: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-6-(((((3-(methylsulfonyl)-2-oxo-1-imidazolidinyl)carbonyl)amino)phenylacetyl)amino)-7-oxo-, (2S-(2alpha,5alpha,6beta(S*)))-, 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanic acid, Meslocillin 
A broad-spectrum, beta-lactam penicillin antibiotic with antibacterial activity. Mezlocillin binds to and inactivates penicillin-binding proteins… 
National Institutes of Health

Related topics

Related topics

22 relations

Broader (1)

Anti-Bacterial Agents
HypersensitivityIn BloodMezlocillin:MCnc:Pt:Ser/Plas:QnMezlocillin:Mass:Pt:Dose:Qn

Narrower (3)

MezlinMezlocillin Sodiumoptocillin

Papers overview

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Highly Cited
1986
Highly Cited
1986
Comparative activities of the beta-lactamase inhibitors YTR 830, clavulanate, and sulbactam combined with ampicillin and broad-spectrum penicillins against defined beta-lactamase-producing aerobic…
The in vitro synergistic activities of the beta-lactamase inhibitors YTR 830, clavulanate, and sulbactam, combined with… 
1984
1984
Comparison of the effects of mezlocillin, carbenicillin, and placebo on normal hemostasis
Mezlocillin was compared with carbenicillin and 0.9% NaCl as placebo in a double-blind manner to determine its effect in vivo on… 
1984
1984
Pseudomonas aeruginosa beta-lactamase as a defence against azlocillin, mezlocillin and piperacillin.
Azlocillin, mezlocillin and piperacillin are weak substrates for the chromosomal beta-lactamase of Pseudomonas aeruginosa, and… 
1983
1983
The effects of mezlocillin, ticarcillin and placebo on blood coagulation and bleeding time in normal volunteers.
Bleeding time, coagulation tests and platelet aggregation response to adenosine diphosphate (ADP), epinephrine, arachidonic acid… 
1983
1983
A comparison of the effects of mezlocillin and carbenicillin on haemostasis in volunteers.
Mezlocillin and carbenicillin were administered intravenously to healthy male volunteers, for six days each, in a double-blind… 
1982
1982
Dose-dependent pharmacokinetics of azlocillin compared to mezlocillin.
The pharmacokinetics of azlocillin at intravenous doses of 1.0, 2.0 and 5.0 g and of 2.0 g mezlocillin were studied in a cross… 
Highly Cited
1981
Highly Cited
1981
Quality control limits for ampicillin, carbenicillin, mezlocillin, and piperacillin disk diffusion susceptibility tests: a collaborative study
A multilaboratory in vitro study was carried out to determine disk diffusion susceptibility testing quality control limits for… 
1981
1981
In vitro inactivation of gentamicin, tobramycin, and netilmicin by carbenicillin, azlocillin, or mezlocillin.
The in vitro inactivation of gentamicin, tobramycin, and netilmicin, when combined with carbenicillin, azlocillin, and… 
1980
1980
Biliary elimination of mezlocillin: an experimental and clinical study
The biliary elimination of mezlocillin, a new semisynthetic penicillin of the acyl-ureido-penicillin group, was investigated in… 
1980
1980
Comparative in vitro activity of cefotaxime (HR 756).
The in vitro activity of cefotaxime (HR 756) was tested in comparison with cefuroxime, cefamondole, cefoxitin, cefazolin…