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Anaerobic metabolism of hydrocarbons proceeds either via addition to fumarate or by hydroxylation in various microorganisms, e.g… Expand In order to study the transport of dicarboxylic acids through the contraluminal cell membrane of proximal tubular cells,3H… Expand The transport of dicarboxylic acids in the proximal convolution was investigated by measuring: a) the zero net flux transtubular… Expand AbstractIn order to study the specificity for contraluminal para-aminohippurate (PAH) transport, the inhibitory potency of… Expand Basolateral uptake of organic anions in renal proximal tubule cells is indirectly coupled to the Na(+) gradient through Na… Expand Mercuric ions are highly reactive and form a variety of organic complexes or conjugates in vivo. The renal proximal tubule is a… Expand Anaerobic microbial toluene catabolism is initiated by addition of fumarate to the methyl group of toluene, yielding (R… Expand Mitochondrial dysfunction due to alterations in the mitochondrial genome (mtDNA) has recently attracted much attention, with the… Expand A neonate with signs of neurologic dysfunction was noted to have elevated blood lactic acid levels. Organic acid analysis… Expand We describe two patients with short-chain acyl-coenzyme A (CoA) dehydrogenase (SCADH) deficiency. Neonate I excreted large… Expand