Methenyltetrahydrofolate cyclohydrolase

Known as: Cyclohydrolase, 5,10-MTHF, 5,10 Methenyltetrahydrofolate Cyclohydrolase, 5,10-MTHF Cyclohydrolase 
An aminohydrolase that catalyzes the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate. In most higher eucaryotic organisms… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1969-2017
05101519692017

Papers overview

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Highly Cited
2002
Highly Cited
2002
Women who take folic acid periconceptionally reduce their risk of having a child with a neural tube defect (NTD) by >50%. A… (More)
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2002
2002
Folate-dependent enzymes are compartmentalized between the cytoplasm and mitochondria of eukaryotes. The role of mitochondrial… (More)
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Highly Cited
2001
Highly Cited
2001
Ascorbic acid has been shown to stimulate endothelial nitric oxide (NO) synthesis in a time- and concentration-dependent fashion… (More)
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Highly Cited
2001
Highly Cited
2001
(6R)-5,6,7,8-Tetrahydro-biopterin (H(4)B) is essential for the catalytic activity of all NO synthases. The hyperphenylalaninemic… (More)
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Highly Cited
2000
Highly Cited
2000
5-methyltetrahydrofolate (MTHF), the active form of folic acid, has been reported to restore NO status in hypercholesterolemic… (More)
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Highly Cited
2000
Highly Cited
2000
Parkinson's disease (PD), a neurological disease suited to gene therapy, is biochemically characterized by a severe decrease in… (More)
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Highly Cited
1996
Highly Cited
1996
An elevated blood level of homocysteine is associated with arteriosclerosis and thrombosis. The mechanisms by which homocysteine… (More)
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1988
1988
A DNA clone complementary to the messenger RNA encoding the human trifunctional enzyme 5,10-methylenetetrahydrofolate… (More)
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1986
1986
NAD-dependent methylenetetrahydrofolate dehydrogenase is expressed in transformed or established mammalian cell lines in vitro… (More)
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1977
1977
Methylenetetrahydrofolate dehydrogenase, methenyltetrahydrofolate cyclohydrolase, and formyltetrahydrofolate synthetase from… (More)
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