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Methallibure

Known as: 1,2-Hydrazinedicarbothioamide, N-methyl-N'-(1-methyl-2-propenyl)-, Metallibur, Metallibure 
A dithiobiurea compound with anti-gonadotropic activity.
National Institutes of Health

Related topics

Related topics

12 relations

Narrower (4)

AimaxICI-33,828SuisynchronTurisynchron

Broader (1)

Hormone Antagonists
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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1977
1977
Effect of methallibure on gonadotrophic content, ovarian 32P uptake and gonadosomatic index in the freshwater catfish, Heteropneustes fossilis (Bloch).
Gonadotrophin content in the pituitary gland and blood serum as well as ovarian 32P uptake were studied in response to… 
1976
1976
Cytology of the anterior pituitary at different times of the year in normal and methallibure-treated male Columbian black-tailed deer (Odocoileus hemionus columbianus).
The application of histochemical staining techniques to the anterior pituitary revealed the presence of seven cell types. Most… 
1975
1975
The effects of Methallibure (ICI 33,828) on the LH release in castrate male rats challenged with LHRH.
Daily administration of 10 mg of Methallibure (ICI 33,828) for 6 days to male castrate rats resulted in significant depression of… 
1973
1973
Antiovulatory effect of ICI 33,828 (methallibure) without affecting prolactin release in normal rats.
The acute effect of 1-alpha-methylallylthiocarbamoyl-2-methylthiocarbamoylhydrazine (methall ibure) on the release of… 
1971
1971
Observations on the anti-gestation effect of Aimax (methallibure) in recently bred gilts.
AN ANTI-GESTATION effect has been reported by Barker (1) in recently bred gilts fed Aimax.1 It was suggested (1) that the first… 
1969
1969
Deformities in piglets following administration of methallibure during specific stages of gestation.
Paget, Walpole & Richardson (1961) reported that the oral administration of the hydrazine derivative methallibure (1-\g=a\-methyl… 
1969
1969
Effect of methallibure (ICI 33,828) on the nitrogen retention and growth induced by ovine growth hormone.
Ovine growth hormone (100-500 I¼g. on alternate days for â�¼22 days) induced N retention and body growth in young rats. This… 
1969
1969
Some effects of a single injection of chlormadinone acetate or methallibure on sexual function in the pubescent male animal. I. The ram.
Chlormadinine acetate (CAP) has both progestational and antiandrogenic activity but is not estrogenic. Methallibure causes… 
1969
1969
The effects of I.C.I. compound 33828 (methallibure) on the production of semen and health of boars.
RECENTLY there has been renewed interest in the problem of male fertility. There is much to be learned about the special… 
1968
1968
Effect of the pituitary inhibitor I.C.I. 33,828 (methallibure) on the reproductive system of male rats.
The effect of treatment with methallibure on the reproductive system of male rats was studied. The drug caused arrest of…