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Mesangial Proliferative Glomerulonephritis

Known as: GLOMERULONEPHRITIS, MESANGIAL PROLIFERATIVE 
A focal inflammation of glomeruli secondary to mesangial cell proliferation and matrix deposition within the mesangium.
National Institutes of Health

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GlomerulonephritisInflammationKidneyUrinary system

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
Fractalkine expression and the recruitment of CX3CR1+ cells in the prolonged mesangial proliferative glomerulonephritis.
BACKGROUND We established the reversible and the prolonged models of mesangial proliferative glomerulonephritis (GN) with anti… 
Highly Cited
2001
Highly Cited
2001
PDGF signal transduction inhibition ameliorates experimental mesangial proliferative glomerulonephritis.
BACKGROUND Platelet-derived growth factor (PDGF) has been consistently implicated in the cell proliferation and extracellular… 
Highly Cited
1997
Highly Cited
1997
Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin-dependent kinase antagonist.
Glomerular injury is characterized by mesangial cell (MC) proliferation and matrix formation. We sought to determine if reducing… 
Highly Cited
1997
Highly Cited
1997
The role of complement in the pathogenesis of tubulointerstitial lesions in rat mesangial proliferative glomerulonephritis.
Persistent proteinuria and tubulointerstitial lesions are important signs of progressive renal disease. The purpose of this study… 
Highly Cited
1996
Highly Cited
1996
Changes in cell-cycle protein expression during experimental mesangial proliferative glomerulonephritis.
A characteristic response to mesangial cell injury is proliferation, which is closely linked to mesangial matrix accumulation and… 
Highly Cited
1995
Highly Cited
1995
Angiotensin II stimulates interleukin-6 release from cultured mouse mesangial cells.
Interleukin-6 (IL-6) is a multifunctional cytokine exerting a wide variety of biologic responses, including cell proliferation… 
Highly Cited
1993
Highly Cited
1993
Increased expression of monocyte chemoattractant protein-1 in anti-thymocyte antibody-induced glomerulonephritis.
The infiltration of monocytes-macrophages in the glomerulus is one of the hallmarks of glomerulonephritis and may play an… 
Highly Cited
1991
Highly Cited
1991
Platelet-derived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat.
We investigated whether platelet-derived growth factor (PDGF), or its receptor (PDGF-R), was upregulated in a rat model of… 
Highly Cited
1991
Highly Cited
1991
Platelet-derived growth factor expression in mesangial proliferative glomerulonephritis.
Proliferation of mesangial cells and expansion of mesangial matrix are common histologic features of proliferative glomerular… 
Highly Cited
1989
Highly Cited
1989
Involvement of IL-6 in mesangial proliferative glomerulonephritis.
In this study, we demonstrated that IL-6 was a possible autocrine growth factor for rat mesangial cells (MC). rIL-6 induced in… 
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