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Mesangial Proliferative Glomerulonephritis

Known as: GLOMERULONEPHRITIS, MESANGIAL PROLIFERATIVE 
A focal inflammation of glomeruli secondary to mesangial cell proliferation and matrix deposition within the mesangium.
National Institutes of Health

Papers overview

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Highly Cited
2001
Highly Cited
2001
Proliferation of mesangial cells is a hallmark of glomerular disease, and understanding its regulatory mechanism is clinically… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Platelet-derived growth factor (PDGF) has been consistently implicated in the cell proliferation and extracellular… Expand
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Highly Cited
1997
Highly Cited
1997
Glomerular injury is characterized by mesangial cell (MC) proliferation and matrix formation. We sought to determine if reducing… Expand
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Highly Cited
1996
Highly Cited
1996
A characteristic response to mesangial cell injury is proliferation, which is closely linked to mesangial matrix accumulation and… Expand
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Highly Cited
1995
Highly Cited
1995
Interleukin-6 (IL-6) is a multifunctional cytokine exerting a wide variety of biologic responses, including cell proliferation… Expand
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Review
1993
Review
1993
Mesangial proliferative glomerulonephritis (mesPGN) is histologically characterized by proliferation of mesangial cells (MC… Expand
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Highly Cited
1993
Highly Cited
1993
The infiltration of monocytes-macrophages in the glomerulus is one of the hallmarks of glomerulonephritis and may play an… Expand
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Highly Cited
1991
Highly Cited
1991
We investigated whether platelet-derived growth factor (PDGF), or its receptor (PDGF-R), was upregulated in a rat model of… Expand
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Highly Cited
1991
Highly Cited
1991
Proliferation of mesangial cells and expansion of mesangial matrix are common histologic features of proliferative glomerular… Expand
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Highly Cited
1989
Highly Cited
1989
In this study, we demonstrated that IL-6 was a possible autocrine growth factor for rat mesangial cells (MC). rIL-6 induced in… Expand
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