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Mepivacaine

Known as: DL-Mepivacaine, Mepivacaina, (+-)-1-Methyl-2',6'-pipecoloxylidide 
An amide-type local anesthetic agent. At the injection site, mepivacaine binds to specific voltage-gated sodium ion channels in neuronal cell… 
National Institutes of Health

Related topics

Related topics

29 relations
1.7 ML Mepivacaine Hydrochloride 30 MG/ML Cartridge [Scandonest]30 ML Mepivacaine Hydrochloride 15 MG/ML Injection [Carbocaine]AmidesDrug Allergy
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Narrower (11)

CarbocaineIsocaineMeaverinMecain
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Broader (1)

Local Anesthetics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Detection of pharmaceutically active compounds in the rivers and tap water of the Madrid Region (Spain) and potential ecotoxicological risk.
Review
2010
Review
2010
Dexamethasone Added to Mepivacaine Prolongs the Duration of Analgesia After Supraclavicular Brachial Plexus Blockade
Background and objectives: Corticosteroids have been used successfully to prolong the duration of local anesthetic action after… 
Highly Cited
2006
Highly Cited
2006
Successful use of a 20% lipid emulsion to resuscitate a patient after a presumed bupivacaine-related cardiac arrest.
The patient was a 58-yr-old, 82-kg, 170-cm male who presented for arthroscopic repair of a torn rotator cuff in the right… 
Highly Cited
2004
Highly Cited
2004
New trend in sample preparation: on-line microextraction in packed syringe for liquid and gas chromatography applications. I. Determination of local anaesthetics in human plasma samples using gas…
  • M. Abdel-Rehim
  • Journal of chromatography. B, Analytical…
  • 2004
  • Corpus ID: 20279866
Review
2003
Review
2003
Delayed Drug Hypersensitivity Reactions
  • W. Pichler
  • Annals of Internal Medicine
  • 2003
  • Corpus ID: 5722186
Drug-induced adverse reactions are a major health problem (1-3). Most adverse effects, so-called type A reactions, are due to the… 
Review
2000
Review
2000
Ropivacaine: an update of its use in regional anaesthesia.
UNLABELLED Ropivacaine is a long-acting, enantiomerically pure (S-enantiomer) amide local anaesthetic with a high pKa and low… 
Highly Cited
1999
Highly Cited
1999
Epidural block with mepivacaine before surgery reduces long-term post-thoracotomy pain
PurposeTo examine the effect of continuous epidural block initiated before thoracic surgery upon early and long-term… 
Highly Cited
1999
Highly Cited
1999
Tramadol added to mepivacaine prolongs the duration of an axillary brachial plexus blockade.
UNLABELLED Tramadol is an analgesic drug that is antagonized by alpha2-adrenoceptor antagonists, as well as opioid antagonists… 
Highly Cited
1996
Highly Cited
1996
A Minimum Dose of Clonidine Added to Mepivacaine Prolongs the Duration of Anesthesia and Analgesia After Axillary Brachial Plexus Block
This study assessed the minimum dose of clonidine required to prolong the duration of both anesthesia and analgesia after… 
Highly Cited
1978
Highly Cited
1978
THE MECHANISM OF PLACEBO ANALGESIA
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