Menthol

Known as: Cyclohexanol, 5-methyl-2-(1-methylethyl)-, Menthol [Chemical/Ingredient], Menthol, unspecified form 
A substance that comes from mint oils or is made in the laboratory. It is used to relieve itching and to treat problems in the upper respiratory… (More)
National Institutes of Health

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1,2,4-trihydroxymenthaneEucalyptamintListerine AntisepticVicks Vaporub
Calcium Carbonate 497 MG / Sodium Bicarbonate 600 MG Oral PowderCamphor 0.05 MG/MG / Menthol 0.034 MG/MG Medicated PatchCamphor 100 MG/ML / Menthol 150 MG/ML / methyl salicylate 330 MG/ML Topical OilCamphor 43.8 MG / Menthol 37 MG / methyl salicylate 72.4 MG Medicated Patch
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Papers overview

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Highly Cited
2008
Highly Cited
2008
Identification of transmembrane domain 5 as a critical molecular determinant of menthol sensitivity in mammalian TRPA1 channels.
TRPA1 is a member of the transient receptor potential (TRP) family of ion channels and is expressed in a subset of nociceptive… (More)
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Highly Cited
2007
Highly Cited
2007
The menthol receptor TRPM8 is the principal detector of environmental cold
Sensory nerve fibres can detect changes in temperature over a remarkably wide range, a process that has been proposed to involve… (More)
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Highly Cited
2007
Highly Cited
2007
Bimodal action of menthol on the transient receptor potential channel TRPA1.
TRPA1 is a calcium-permeable nonselective cation transient receptor potential (TRP) channel that functions as an excitatory… (More)
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Highly Cited
2006
Highly Cited
2006
More than cool: Promiscuous relationships of menthol and other sensory compounds
Several temperature-activated transient receptor potential (thermoTRP) ion channels are the molecular receptors of natural… (More)
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Highly Cited
2004
Highly Cited
2004
Noxious Cold Ion Channel TRPA1 Is Activated by Pungent Compounds and Bradykinin
Six members of the mammalian transient receptor potential (TRP) ion channels respond to varied temperature thresholds. The… (More)
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Highly Cited
2004
Highly Cited
2004
Topical menthol--a human model for cold pain by activation and sensitization of C nociceptors.
Although cold hyperalgesia is a frequent symptom in patients with neuropathic pain, it is poorly understood. We investigated the… (More)
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Highly Cited
2003
Highly Cited
2003
ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures
Mammals detect temperature with specialized neurons in the peripheral nervous system. Four TRPV-class channels have been… (More)
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Highly Cited
2002
Highly Cited
2002
A TRP Channel that Senses Cold Stimuli and Menthol
A distinct subset of sensory neurons are thought to directly sense changes in thermal energy through their termini in the skin… (More)
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Highly Cited
2002
Highly Cited
2002
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
The cellular and molecular mechanisms that enable us to sense cold are not well understood. Insights into this process have come… (More)
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Highly Cited
2002
Highly Cited
2002
A cold- and menthol-activated current in rat dorsal root ganglion neurones: properties and role in cold transduction.
Skin temperature is sensed by peripheral thermoreceptors. Using the neuronal soma in primary culture as a model of the receptor… (More)
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