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Herbs and spices containing essential oils (EOs) in the range of 0.05–0.1% have demonstrated activity against pathogens, such as… Expand Sensory nerve fibres can detect changes in temperature over a remarkably wide range, a process that has been proposed to involve… Expand TRPA1 is a calcium-permeable nonselective cation transient receptor potential (TRP) channel that functions as an excitatory… Expand Several temperature-activated transient receptor potential (thermoTRP) ion channels are the molecular receptors of natural… Expand Six members of the mammalian transient receptor potential (TRP) ion channels respond to varied temperature thresholds. The… Expand Mammals detect temperature with specialized neurons in the peripheral nervous system. Four TRPV-class channels have been… Expand A distinct subset of sensory neurons are thought to directly sense changes in thermal energy through their termini in the skin… Expand Menthol, after topical application, causes a feeling of coolness due to stimulation of 'cold' receptors by inhibiting Ca… Expand The cellular and molecular mechanisms that enable us to sense cold are not well understood. Insights into this process have come… Expand Summary— Menthol and related cooling compounds such as ‘coolant agent 10’, are widely used in products ranging from common cold… Expand