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Megaloblastic Anemia due to Dihydrofolate Reductase Deficiency

Known as: DHFR DEFICIENCY 
National Institutes of Health

Related topics

Related topics

13 relations
Absence EpilepsyAnemia, MegaloblasticAtaxiaAutosomal recessive inheritance

Broader (1)

Tetrahydrofolate Dehydrogenase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
ED-10ASSOCIATIONS BETWEEN MATERNAL AND INHERITED GENETIC VARIATION IN FOLATE METABOLISM GENES AND PEDIATRIC BRAIN TUMORS IN A HIGH RISK POPULATION: A PILOT STUDY
Folic acid is critically important for normal neural development and has been implicated in pediatric brain tumor (PBT) risk… 
2013
2013
Pharmacogenomic Assessment of Outcomes of Pemetrexed-Treated Patients with Adenocarcinoma of the Lung
Purpose The main objective of this study was to evaluate the association between polymorphisms of the target genes of pemetrexed… 
2013
2013
Abstract 2369: Pharmacogenomic assessment of outcomes of pemetrexed-treated patients with adenocarcinoma of the lung.
Purpose: The main objective of this study was to evaluate the association between polymorphisms of the target genes of pemetrexed… 
2008
2008
Directed Evolution and Osmolyte Studies of R67 Dihydrofolate Reductase
The plasmid-encoded Escherichia coli enzyme R67 dihydrofolate reductase (DHFR) provides resistance to the antibiotic trimethoprim… 
1999
1999
Use of Computational Docking Procedure to Identify Potential Inhibitors of R67 Dihydrofolate Reductase
Indiscriminate use of antibiotics has created a selective advantage for resistant strains of bacteria. Resistance is spread… 
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