Tetrahydrofolate Dehydrogenase

Known as: Reductase, Dihydrofolate, Tetrahydrofolate Dehydrogenase [Chemical/Ingredient], Dihydrofolate Dehydrogenase 
An enzyme of the oxidoreductase class that catalyzes the reaction 7,8-dihyrofolate and NADPH to yield 5,6,7,8-tetrahydrofolate and NADPH+, producing… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Antibiotic resistance can evolve through the sequential accumulation of multiple mutations. To study such gradual evolution, we… (More)
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Highly Cited
2006
Highly Cited
2006
This protocol describes a method of genetic transformation for the rodent malaria parasite Plasmodium berghei with a high… (More)
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Highly Cited
2003
Highly Cited
2003
A genetic dimorphism encodes for either alanine (Ala) or valine (Val) in the mitochondrial targeting sequence (MTS) of human… (More)
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Highly Cited
2003
Highly Cited
2003
Malaria parasites (Plasmodium falciparum) provide an excellent system in which to study the genomic effects of strong selection… (More)
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Highly Cited
1997
Highly Cited
1997
Increasing resistance of Plasmodium falciparum malaria parasites to chloroquine and the dihydrofolate reductase (DHFR) inhibitors… (More)
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Highly Cited
1996
Highly Cited
1996
We report a new method for in situ localization of DNA sequences that allows excellent preservation of nuclear and chromosomal… (More)
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Highly Cited
1992
Highly Cited
1992
Five new binary vectors have been constructed which have the following features: (1) different plant selectable markers including… (More)
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Highly Cited
1991
Highly Cited
1991
The promoter of the human dihydrofolate reductase (DHFR) gene contains two consensus binding sites for the DNA binding protein… (More)
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Highly Cited
1988
Highly Cited
1988
We describe the isolation and the sequence of the gene for the bifunctional enzyme dihydrofolate reductase-thymidylate synthase… (More)
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Highly Cited
1987
Highly Cited
1987
We find a dramatic difference in the efficiency of removal of UV-induced pyrimidine dimers from the transcribed and… (More)
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