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Mediastinal (Thymic) Large B-Cell Lymphoma

Known as: Primary Mediastinal Large B-Cell Lymphoma, Mediastinal large B-cell lymphoma, PMBL 
A large B-cell non-Hodgkin lymphoma arising in the mediastinum. Morphologically it is characterized by a massive diffuse lymphocytic proliferation… 
National Institutes of Health

Related topics

Related topics

29 relations
Atypical lymphocyteB lymphoblastB-LymphocytesBCL6 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Expression of Programmed Cell Death 1 Ligand 2 (PD-L2) Is a Distinguishing Feature of Primary Mediastinal (Thymic) Large B-cell Lymphoma and Associated With PDCD1LG2 Copy Gain
Primary mediastinal (thymic) large B-cell lymphoma (PMBL) and diffuse large B-cell lymphoma (DLBCL) are tumors with distinct… 
Highly Cited
2013
Highly Cited
2013
Genomic rearrangements involving programmed death ligands are recurrent in primary mediastinal large B-cell lymphoma.
The pathogenesis of primary mediastinal large B-cell lymphoma (PMBCL) is incompletely understood. Recently, specific genotypic… 
Highly Cited
2010
Highly Cited
2010
Cooperative epigenetic modulation by cancer amplicon genes.
Highly Cited
2009
Highly Cited
2009
TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma
Proliferation and survival of Hodgkin and Reed/Sternberg (HRS) cells, the malignant cells of classical Hodgkin lymphoma (cHL… 
Review
2006
Review
2006
Favorable outcome of primary mediastinal large B-cell lymphoma in a single institution: the British Columbia experience.
BACKGROUND Primary mediastinal large B-cell lymphoma (PMBCL) is a distinct clinico-pathological subtype of diffuse large B-cell… 
Highly Cited
2005
Highly Cited
2005
BIC and miR‐155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas
In a previous study we demonstrated high expression of the non‐coding BIC gene in the vast majority of Hodgkin's lymphomas (HLs… 
Highly Cited
2005
Highly Cited
2005
NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes.
Primary mediastinal large B-cell lymphoma (MLBCL) shares important clinical and molecular features with classic Hodgkin lymphoma… 
Highly Cited
2003
Highly Cited
2003
The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma.
Mediastinal large B-cell lymphoma (MLBCL) is a recently identified subtype of diffuse large B-cell lymphoma (DLBCL) that… 
Review
1999
Review
1999
CNS involvement in primary mediastinal large B-cell lymphoma.
PURPOSE The risk of CNS involvement by non-Hodgkin's Lymphoma (NHL) has been associated with bone marrow and/or testicular… 
Highly Cited
1996
Highly Cited
1996
Primary mediastinal large B-cell lymphoma. A clinicopathologic study of 141 cases compared with 916 nonmediastinal large B-cell lymphomas, a GELA ("Groupe d'Etude des Lymphomes de l'Adulte") study.
Among non-Hodgkin's lymphomas, primary mediastinal large B-cell lymphoma (PMLCL) has been considered a separate entity that has… 
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