Matrix Metalloproteinase 7 Measurement

Known as: MMP7, Matrilysin, Matrix Metalloproteinase 7 
The determination of the amount of matrix metalloproteinase 7 present in a sample.
National Institutes of Health

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CDISC SDTM Laboratory Test Terminology by CodeCDISC SDTM Laboratory Test Terminology by NameClinical Data Interchange Standards Consortium TerminologyMMP7 gene
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Highly Cited
2005
Highly Cited
2005
The catenin p120ctn inhibits Kaiso-mediated transcriptional repression of the beta-catenin/TCF target gene matrilysin.
The POZ-zinc finger transcription factor Kaiso was first identified as a specific binding partner for the Armadillo catenin and… (More)
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Highly Cited
2003
Highly Cited
2003
Matrilysin (matrix metalloproteinase-7) mediates E-cadherin ectodomain shedding in injured lung epithelium.
Matrilysin (matrix metalloproteinase-7) is highly expressed in lungs of patients with pulmonary fibrosis and other conditions… (More)
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Highly Cited
2002
Highly Cited
2002
CD44 anchors the assembly of matrilysin/MMP-7 with heparin-binding epidermal growth factor precursor and ErbB4 and regulates female reproductive organ remodeling.
CD44 is a facultative proteoglycan implicated in cell adhesion and trafficking, as well as in tumor survival and progression. We… (More)
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Highly Cited
2002
Highly Cited
2002
Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans.
Pulmonary fibrosis is a progressive and largely untreatable group of disorders that affects up to 100,000 people on any given day… (More)
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Highly Cited
2001
Highly Cited
2001
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: clinicopathologic and prognostic significance of matrilysin expression.
PURPOSE A disruption in the balance between the matrix metalloproteinases (MMPs) and their natural inhibitors, tissue inhibitors… (More)
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Highly Cited
1999
Highly Cited
1999
The metalloproteinase matrilysin is a target of β-catenin transactivation in intestinal tumors
Matrilysin is a matrix metalloproteinase expressed in the tumor cells of greater than 80% of intestinal adenomas. The majority of… (More)
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Highly Cited
1999
Highly Cited
1999
The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis
BACKGROUND The Fas ligand/Fas receptor (FasL/Fas) system is an important mediator of apoptosis in the immune system where the… (More)
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Highly Cited
1999
Highly Cited
1999
Contribution of matrilysin (MMP-7) to the metastatic pathway of human colorectal cancers.
BACKGROUND/AIM Matrilysin is one of the matrix metalloproteinases that has a critical role in tumour invasion, and is often… (More)
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Highly Cited
1997
Highly Cited
1997
Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin.
Matrix metalloproteinases (MMPs) classically have been implicated in basement membrane destruction associated with late-stage… (More)
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Review
1996
Review
1996
Matrilysin: an epithelial matrix metalloproteinase with potentially novel functions.
Matrilysin (MAT) is a member of the matrix metalloproteinase (MMP) family which is believed to degrade components of the… (More)
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