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Mastermind-Like Protein 2

Known as: MAML2, Mam-2 
Mastermind-like protein 2 (1156 aa, ~125 kDa) is encoded by the human MAML2 gene. This protein plays a role in the mediation of transcription.
National Institutes of Health

Related topics

Related topics

10 relations
AdenolymphomaClear cell hidradenomaGenes, RegulatorMAML2 gene

Papers overview

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Highly Cited
2017
Highly Cited
2017
MAML2 Rearrangements in Variant Forms of Mucoepidermoid Carcinoma: Ancillary Diagnostic Testing for the Ciliated and Warthin-like Variants
Mucoepidermoid carcinoma (MEC) is the most common salivary gland malignancy. Recent studies have shown that most MECs harbor gene… 
2017
2017
Thyroid sclerosing mucoepidermoid carcinoma with eosinophilia: a clinicopathologic and molecular analysis of a distinct entity
Sclerosing mucoepidermoid carcinoma with eosinophilia is a rare thyroid neoplasm of uncertain pathogenesis that resembles… 
Highly Cited
2016
Highly Cited
2016
Stilbenoids remodel the DNA methylation patterns in breast cancer cells and inhibit oncogenic NOTCH signaling through epigenetic regulation of MAML2 transcriptional activity
Summary We established the role for epigenetics in regulation of NOTCH signaling in breast cancer. This may constitute a common… 
Review
2016
Review
2016
Diagnostic and prognostic utility of Mastermind-like 2 (MAML2) gene rearrangement detection by fluorescent in situ hybridization (FISH) in mucoepidermoid carcinoma of the salivary glands.
2014
2014
Glandular Odontogenic Cysts (GOCs) Lack MAML2 Rearrangements: A Finding to Discredit the Putative Nature of GOC as a Precursor to Central Mucoepidermoid Carcinoma
Glandular odontogenic cyst (GOC) is a cyst of the gnathic bones that is characterized by squamous and glandular differentiation… 
Highly Cited
2013
Highly Cited
2013
Clinicopathological significance of MAML2 gene split in mucoepidermoid carcinoma
CRTC1–MAML2 and CRTC3–MAML2 fusions have been associated with favorable clinicopathological features of mucoepidermoid carcinomas… 
Review
2013
Review
2013
Analysis of MAML2 rearrangement in mucoepidermoid carcinoma of the thymus.
Highly Cited
2009
Highly Cited
2009
Mucoepidermoid Carcinoma of the Cervix: Another Tumor With the t(11;19)-associated CRTC1-MAML2 Gene Fusion
Mucoepidermoid carcinoma (MEC) of the uterine cervix is a controversial entity. By strict morphologic criteria, the tumor has… 
Highly Cited
2008
Highly Cited
2008
A new type of MAML2 fusion in mucoepidermoid carcinoma
The present study reports for the first time a CRTC3‐MAML2 fusion gene in a mucoepidermoid carcinoma, as determined by RT‐PCR and… 
Highly Cited
2005
Highly Cited
2005
Transforming activity of MECT1‐MAML2 fusion oncoprotein is mediated by constitutive CREB activation
Salivary gland tumors, a group of histologically diverse benign and malignant neoplasms, represent a challenging problem for… 
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