Malignant Pineal Region Germ Cell Tumor

Known as: Malignant Pineal Gland Germ Cell Neoplasm, Malignant Pineal Parenchymal Germ Cell Neoplasm, Malignant Germ Cell Tumor of the Pineal Parenchyma 
A malignant germ cell tumor that arises in the pineal region. Representative examples include germinoma, immature teratoma, choriocarcinoma… (More)
National Institutes of Health

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BrainCentral Nervous SystemGerm CellsGerminal Layer
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Papers overview

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Highly Cited
2003
Highly Cited
2003
Principles of treatment of the pineal region tumors.
BACKGROUND A pineal region tumor is an uncommon deep-seated, heterogeneous group of mass lesions of the brain, and the management… (More)
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Highly Cited
2003
Highly Cited
2003
dead end, a Novel Vertebrate Germ Plasm Component, Is Required for Zebrafish Primordial Germ Cell Migration and Survival
In most animals, primordial germ cell (PGC) specification and development depend on maternally provided cytoplasmic determinants… (More)
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Highly Cited
2000
Highly Cited
2000
Zebrafish vasa RNA but Not Its Protein Is a Component of the Germ Plasm and Segregates Asymmetrically before Germline Specification
Work in different organisms revealed that the vasa gene product is essential for germline specification. Here, we describe the… (More)
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Highly Cited
2000
Highly Cited
2000
A critical role for Xdazl, a germ plasm-localized RNA, in the differentiation of primordial germ cells in Xenopus.
Xdazl is an RNA component of Xenopus germ plasm and encodes an RNA-binding protein that can act as a functional homologue of… (More)
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Highly Cited
1998
Highly Cited
1998
Zebrafish organizer development and germ-layer formation require nodal-related signals
The vertebrate body plan is established during gastrulation, when cells move inwards to form the mesodermal and endodermal germ… (More)
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Highly Cited
1998
Highly Cited
1998
Regulation of zygotic gene expression in Drosophila primordial germ cells
Activation of the zygotic genome is a prerequisite for the transition from maternal to zygotic control of development. The onset… (More)
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Highly Cited
1996
Highly Cited
1996
Essential role of the posterior morphogen nanos for germline development in Drosophila
IN many animal groups, factors required for germline formation are localized in germ plasm1, a region of the egg cytoplasm. In… (More)
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Review
1994
Review
1994
The embryonic vertebrate forebrain: the prosomeric model.
C. elegans early embryos extends beyond the parallels between hunchback and glp-1 translational regulation. Both embryos contain… (More)
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Review
1993
Review
1993
Melatonin, hydroxyl radical-mediated oxidative damage, and aging: a hypothesis.
Melatonin is a very potent and efficient endogenous radical scavenger. The pineal indolamine reacts with the highly toxic… (More)
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Highly Cited
1990
Highly Cited
1990
RFLP analysis of phylogenetic relationships and genetic variation in the genus Lycopersicon
Forty single-copy, nuclear probes of known chromosomal position were used to examine restriction fragment length polymorphism in… (More)
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