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Maleimide

 

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Topic mentions per year

1948-2017
0102019482016

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Maleimides

Related mentions per year

Related mentions per year

1949-2018
19401960198020002020
Maleimide
Maleimides

Papers overview

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2014
2014
Self-hydrolyzing maleimides improve the stability and pharmacological properties of antibody-drug conjugates
Many antibody-drug conjugates (ADCs) are unstable in vivo because they are formed from maleimide-containing components conjugated… (More)
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2013
2013
A novel application of maleimide for advanced drug delivery: in vitro and in vivo evaluation of maleimide-modified pH-sensitive liposomes
Maleimide is a stable and easy-to-handle moiety that rapidly and covalently conjugates thiol groups of cysteine residues in… (More)
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2009
2009
Synthesis of Maleimide-End Functionalized Star Polymers and Multimeric Protein-Polymer Conjugates.
Protein-polymer conjugates exhibit superior properties to unmodified proteins, generating a high demand for these materials in… (More)
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2008
2008
N-arachidonyl maleimide potentiates the pharmacological and biochemical effects of the endocannabinoid 2-arachidonylglycerol through inhibition of monoacylglycerol lipase.
Inhibition of the metabolism of the endocannabinoids, anandamide (AEA) and 2-arachidonyl glycerol (2-AG), by their primary… (More)
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2007
2007
Peptide surface modification of methacrylamide chitosan for neural tissue engineering applications.
Nerve fibres are guided to their targets by the combined actions of chemotactic and haptotactic stimuli; however, translating… (More)
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2003
2003
Maleimide-oligo(ethylene glycol) derivatives of camptothecin as albumin-binding prodrugs: synthesis and antitumor efficacy.
In situ binding of thiol-reactive prodrugs to the cysteine-34 position of circulating albumin is a new approach in drug delivery… (More)
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2003
2003
Why asparagine needs carbohydrates to generate acrylamide.
Structural considerations dictate that asparagine alone may be converted thermally into acrylamide through decarboxylation and… (More)
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2000
2000
A novel macromolecular prodrug concept exploiting endogenous serum albumin as a drug carrier for cancer chemotherapy.
Introduction. Serum proteins are potential drug carriers of antineoplastic agents due to their accumulation in tumor tissue.1… (More)
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1984
1984
More useful maleimide compounds for the conjugation of Fab' to horseradish peroxidase through thiol groups in the hinge.
Nine different maleimide compounds were evaluated for the conjugation of Fab' to horseradish peroxidase through thiol groups in… (More)
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1984
1984
Kinetics and mechanism of the alkaline hydrolysis of maleimide.
The kinetics of hydrolysis of maleimide was carried out within the [OH-] range of 2.46 X 10(-6) to 2.0 M at 30 degrees C. The… (More)
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