Malate Synthase

Known as: Malate Condensing Enzyme, Glyoxylate Transacetylase, Synthase, Malate 
An important enzyme in the glyoxylic acid cycle which reversibly catalyzes the synthesis of L-malate from acetyl-CoA and glyoxylate. This enzyme was… (More)
National Institutes of Health

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Review
2009
Review
2009
Major roles of isocitrate lyase and malate synthase in bacterial and fungal pathogenesis.
The glyoxylate cycle is an anaplerotic pathway of the tricarboxylic acid (TCA) cycle that allows growth on C(2) compounds by… (More)
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Highly Cited
2009
Highly Cited
2009
Aluminum-activated citrate and malate transporters from the MATE and ALMT families function independently to confer Arabidopsis aluminum tolerance.
Aluminum-activated root malate and citrate exudation play an important role in plant Al tolerance. This paper characterizes… (More)
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2006
2006
Mycobacterium tuberculosis malate synthase is a laminin-binding adhesin.
Mycobacterium tuberculosis (M. tb) uses the glyoxalate bypass for intracellular survival in vivo. These studies provide evidence… (More)
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Highly Cited
2005
Highly Cited
2005
Arabidopsis peroxisomal citrate synthase is required for fatty acid respiration and seed germination.
We tested the hypothesis that peroxisomal citrate synthase (CSY) is required for carbon transfer from peroxisomes to mitochondria… (More)
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Highly Cited
2004
Highly Cited
2004
Pathogenicity of Stagonospora nodorum requires malate synthase.
A gene encoding malate synthase, a key enzyme of the glyoxylate cycle, has been cloned and characterized in the necrotrophic… (More)
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Highly Cited
2003
Highly Cited
2003
Ile, Leu, and Val methyl assignments of the 723-residue malate synthase G using a new labeling strategy and novel NMR methods.
New NMR experiments are presented for the assignment of methyl (13)C and (1)H chemical shifts from Ile, Leu, and Val residues in… (More)
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Highly Cited
2003
Highly Cited
2003
Biochemical and structural studies of malate synthase from Mycobacterium tuberculosis.
Establishment or maintenance of a persistent infection by Mycobacterium tuberculosis requires the glyoxylate pathway. This is a… (More)
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Review
2002
Review
2002
Malate dehydrogenases--structure and function.
Malate dehydrogenases (MDH, L-malate:NAD oxidoreductase, EC 1.1.1.37), catalyze the NAD/NADH-dependent interconversion of the… (More)
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Highly Cited
2001
Highly Cited
2001
The glyoxylate cycle is required for fungal virulence
Candida albicans, a normal component of the mammalian gastrointestinal flora, is responsible for most fungal infections in… (More)
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1994
1994
Molecular characterization of Escherichia coli malate synthase G. Differentiation with the malate synthase A isoenzyme.
Two genes encoding the enzymes malate synthase G and glycolate oxidase, have been linked to locus glc (64.5 min), responsible for… (More)
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