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Osteoarthritis (OA), primarily characterized by cartilage degeneration, is caused by an imbalance between anabolic and catabolic… Expand Keeping Wee1B in the nucleus is important to maintain meiotic arrest, but its timely export is also required for meiosis to… Expand Plk1 (Polo-like kinase 1), an evolutionarily conserved serine/threonine kinase, is crucially involved in multiple events during… Expand The age-associated decrease in the efficiency of CNS remyelination has clear implications for recovery from demyelinating… Expand Activation of Cdc2, is the universal event controlling the onset of mitosis. In higher eukaryotes, Cdc2 activity is in part… Expand M‐phase entry in eukaryotic cells is driven by activation of MPF, a regulatory factor composed of cyclin B and the protein kinase… Expand Activation of the Cdc2·cyclin B kinase is a pivotal step of mitotic initiation. This step is mediated principally by the… Expand X-MyT1 is a C2HC-type zinc finger protein that we find to be involved in the primary selection of neuronal precursor cells in… Expand Cdc2 is the cyclin-dependent kinase that controls entry of cells into mitosis. Phospho-rylation of Cdc2 on threonine-14 and… Expand A novel member of the zinc finger superfamily was cloned by virtue of its binding to cis-regulatory elements of a glia-specific… Expand