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MYSM1 gene

Known as: KIAA1915, Myb-Like, SWIRM and MPN Domains 1 Gene, Myb like, SWIRM and MPN domains 1 
This gene is involved in both the deubiquitination of histone 2A and transcriptional regulation.
National Institutes of Health

Papers overview

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2017
2017
The PROTAC (proteolysis-targeting chimera) ARV-825 recruits bromodomain and extraterminal (BET) proteins to the E3 ubiquitin… Expand
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2017
2017
Myeloproliferative neoplasms with myelofibrosis (MPN-MF) demonstrate constitutive activation of Janus kinase/signal transducer… Expand
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Review
2016
Review
2016
Cohesin is a highly-conserved protein complex that plays important roles in sister chromatid cohesion, chromatin structure, gene… Expand
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2016
2016
p53 is a central mediator of cellular stress responses, and its precise regulation is essential for the normal progression of… Expand
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2015
2015
Pattern-recognition receptors (PRRs) including Toll-like receptors, RIG-I-like receptors, and cytoplasmic DNA receptors are… Expand
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2015
2015
MYSM1 is a chromatin-binding transcriptional cofactor that deubiquitinates histone H2A. Studies of Mysm1-deficient mice have… Expand
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2015
2015
BACKGROUND Myb-Like, SWIRM, and MPN domains 1 (MYSM1) is a metalloprotease that deubiquitinates the K119-monoubiquitinated form… Expand
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2013
2013
Epigenetic histone modifications play critical roles in the control of self-renewal and differentiation of hematopoietic stem… Expand
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2012
2012
Stem cell differentiation and lineage specification depend on coordinated programs of gene expression, but our knowledge of the… Expand
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2011
2011
Epigenetic histone modifications play critical roles in the control of gene transcription. Recently, an increasing number of… Expand
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