Skip to search formSkip to main contentSkip to account menu

MX1 wt Allele

Known as: Myxovirus Resistance 1, Mouse, Homolog of Gene, MxA, Myxovirus (Influenza) Resistance 1, Homolog of Murine (Interferon-Inducible Protein p78) Gene 
Human MX1 wild-type allele is located in the vicinity of 21q22.3 and is approximately 39 kb in length. This allele, which encodes interferon-induced… 
National Institutes of Health

Related topics

Related topics

6 relations
21q22.3Antiviral ResponseApoptosisGTP Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Biological markers of interferon-beta therapy: comparison among interferon-stimulated genes MxA, TRAIL and XAF-1
Biological activity of interferon-beta (IFNβ) can be assessed by measuring IFN-stimulated genes (ISGs). Among them, myxovirus… 
Highly Cited
2005
Highly Cited
2005
Hepatitis C virus core protein down-regulates transcription of interferon-induced antiviral genes.
BACKGROUND Hepatitis C virus (HCV) proteins interfere with the interferon (IFN)-alpha-induced Jak/signal transducer and activator… 
Highly Cited
2005
Highly Cited
2005
The importance of measuring IFNβ bioactivity: Monitoring in MS patients and the effect of anti-IFNβ antibodies
Highly Cited
2000
Highly Cited
2000
Morphometric X‐Ray Absorptiometry and Morphometric Radiography of the Spine: A Comparison of Prevalent Vertebral Deformity Identification
Prevalent vertebral deformities are associated with a substantially increased risk of subsequent vertebral and nonvertebral… 
Highly Cited
2000
Highly Cited
2000
A Monomeric GTPase-Negative MxA Mutant with Antiviral Activity
ABSTRACT MxA is a large, interferon-induced GTPase with antiviral activity against RNA viruses. It forms large oligomers, but… 
Highly Cited
1999
Highly Cited
1999
Correlation of interferon-induced expression of MxA mRNA in peripheral blood mononuclear cells with the response of patients with chronic active hepatitis C to IFN-alpha therapy.
MxA, a protein with selective activity against certain viruses, is an accepted specific indicator of type I interferon (IFN… 
Highly Cited
1998
Highly Cited
1998
A novel bioassay for the determination of neutralizing antibodies to IFN-beta1b.
We have adapted the new MxA gene-induction bioassay to measure neutralizing antibodies to interferon-beta1b (IFN-beta1b, the… 
Highly Cited
1998
Highly Cited
1998
Domains Mediating Intramolecular Folding and Oligomerization of MxA GTPase*
MxA is an interferon-induced GTPase of human cells that inhibits the multiplication of several RNA viruses by a still poorly… 
Highly Cited
1993
Highly Cited
1993
MxA-dependent inhibition of measles virus glycoprotein synthesis in a stably transfected human monocytic cell line
The alpha/beta (type I) interferon-inducible human MxA protein confers resistance to vesicular stomatitis virus (VSV) and… 
Highly Cited
1990
Highly Cited
1990
The human intracellular Mx‐homologous protein is specifically induced by type I interferons
The murine Mx‐1 protein is one of the best biochemically and functionally characterized interferon (IFN)‐induced proteins that is… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)