MX1 gene

Known as: Myxovirus (Influenza Virus) Resistance 1, Interferon-Inducible Protein p78 (Mouse) Gene, INTERFERON-INDUCIBLE PROTEIN p78, MYXOVIRUS RESISTANCE 1, MOUSE, HOMOLOG OF 
This gene plays a role in GTP hydrolysis, interferon signaling and apoptosis.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
BACKGROUND & AIMS Interferon (IFN)-α therapy is not effective for most patients with chronic hepatitis B virus (HBV) infection… (More)
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Highly Cited
2011
Highly Cited
2011
Human CD317 is an intrinsic immunity factor that restricts the release of enveloped viruses, including the major pathogens HIV… (More)
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Highly Cited
2007
Highly Cited
2007
Mice carrying a wild-type Mx1 gene (Mx1+/+) differ from standard laboratory mice (Mx1-/-) in being highly resistant to infection… (More)
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Highly Cited
2007
Highly Cited
2007
The IFN-induced resistance factor Mx1 is a critical component of innate immunity against influenza A viruses (FLUAV) in mice… (More)
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Highly Cited
2005
Highly Cited
2005
Rabies virus (RV) of the Rhabdoviridae family grows in alpha/beta interferon (IFN)-competent cells, suggesting the existence of… (More)
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Highly Cited
2005
Highly Cited
2005
Dendritic cells (DCs) respond to microbial infections by undergoing phenotypic maturation and by producing multiple cytokines. In… (More)
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Highly Cited
2001
Highly Cited
2001
Plasmacytoid dendritic cell (P-DC) precursors in peripheral blood produce large amounts of interferon (IFN)-alpha/beta when… (More)
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Highly Cited
1999
Highly Cited
1999
The type I IFNs represent a primordial, tightly regulated defense system against acute viral infection. IFN-alpha confers… (More)
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Highly Cited
1993
Highly Cited
1993
The role of indoleamine 2,3-dioxygenase (IDO) in IFN-gamma-mediated inhibition of intracellular parasite growth has been examined… (More)
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Highly Cited
1990
Highly Cited
1990
MxA and MxB are interferon-induced proteins of human cells and are related to the murine protein Mx1, which confers selective… (More)
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